Nasogastric tube

1. A method for supplying substances or pressure to a stomach and/or duodenum of a patient, while sealing an esophagus against reflux, the method comprising:

introducing a tube through the esophagus of the patient, said tube comprising:

a main lumen having one or more proximal connectors connectable to a source of substances or pressure and a distal end configured to be positioned within the stomach and/or duodenum when in use, the distal end comprising an opening that during use allows access to the stomach and/or duodenum for the substances or pressure; and

at least four vacuum lumens peripherally surrounding said main lumen, each of said vacuum lumens comprising a vacuum sealing portion; wherein a distance between said opening in the distal end and said vacuum sealing portions is such that when said distal end is positioned within the stomach and/or duodenum, each of said vacuum sealing portions is located within the esophagus, wherein each of said vacuum sealing portions comprises one or more suction ports; and

applying vacuum to said one or more suction ports so as to circumferentially and sealingly draw an inner wall of the esophagus against the one or more suction ports, thereby disabling reflux.

2. The method according to claim 1 , further comprising regulating a vacuum so that a suction level is not constant over time in said vacuum sealing portions.

3. The method of according to claim 1 , wherein said at least four vacuum lumens comprise more than one vacuum sealing portion.

4. The method of claim 3 , further comprising regulating a vacuum to said more than one vacuum sealing portion of said at least four vacuum lumens.

5. The method of claim 4 , wherein regulating the vacuum to said more than one vacuum sealing portion comprises regulating the vacuum so as to create peristaltic movement or other oscillatory movement of the esophagus.

6. The method according to claim 1 , further comprising supplying the substances or pressure to the stomach and/or duodenum of the patient through the opening in the distal end of said tube, while the esophagus is sealed against each of said vacuum sealing portions.

7. The system according to claim 1 , wherein each of said vacuum sealing portions comprises at least two suction ports.

8. The system according to claim 1 , wherein the tube is made from a biocompatible material.

9. The system according to claim 1 , wherein the tube is made from polyurethane, silicone, polyvinyl chloride stainless steel, titanium alloys, nickel titanium, or any combination thereof.

10. The system according to claim 1 , wherein the main lumen has a length of 50 to 130 cm.

11. The system according to claim 1 , wherein the main lumen has an outer diameter in the range of 5-12 Fr.

12. The system according to claim 1 , wherein each said vacuum sealing portion of said at least four vacuum lumens are round or oval.