Extended release formulation
The present invention provides an extended release insecticide formulation, the formulation comprising: an insecticide on a substrate; a lipophilic wax, wherein the insecticide is incorporated into the wax forming a matrix; a release retarding polymer in the matrix; and a rate extending polymer embed the matrix. Methods of making the formulation and use of the formulation are also provided.
1. An extended release insecticide formulation for water applications having efficacy of 35-45 days, the formulation comprising:
a matrix comprising 0.1% to 20% methoprene incorporated into a lipophilic wax applied on a substrate, the matrix further comprising a water erodible powder present at 55% to about 85% w/w, wherein the water erodible powder is calcium sulfate;
a release retarding polymer present at 1% w/w to about 8% w/w together with a rate extending polymer present at 1% w/w to about 10% w/w uniformly embedded in the matrix; and
polyvinyl alcohol (PVA) present at 1% to 15%, wherein the rate extending polymer is a water insoluble alginate within the formulation, which formulation is for use in water and having efficacy of 35-45 days.
2. The extended release insecticide formulation of claim 1 , wherein the substrate is silica.
3. The extended release insecticide formulation of claim 1 , wherein the lipophilic wax is a member selected from the group consisting of an animal wax, a vegetable wax, a petroleum wax, a hydrogenate vegetable oil, or a polyethylene polymer.
4. The extended release insecticide formulation of claim 1 , wherein the lipophilic wax is present in about 1% to about 20% w/w.
5. The extended release insecticide formulation of claim 1 , wherein the release retarding polymer is a member selected from the group consisting of guar gum, xanthan gum, polyurethanes, gelatins, hydroxypropylmethylcellulose, sodium carboxymethylcellulose, methylcellulose, ethylcellulose, hydroxyethyl cellulose, hydroxypropylcellulose, hydroxyethylmethylcellulose, and hydroxypropylethylcellulose, or a combination thereof.
6. The extended release insecticide formulation of claim 1 , wherein the release retarding polymer is xanthan gum.
7. A method for eradicating an insect, the method comprising
contacting the insect with an extended release insecticide formulation according to claim 1 ; to thereby eradicate the insect.
8. The extended release insecticide formulation of claim 1 , wherein the water insoluble alginate within the formulation is calcium alginate.
9. The extended release insecticide formulation of claim 1 , wherein the formulation comprises:
14.5% w/w methoprene-wax silica;
73% w/w calcium sulfate;
1.5% w/w xanthan gum;
4.5% w/w sodium alginate; and
6.5% w/w polyvinyl alcohol (PVA).
10. The extended release insecticide formulation of claim 9 , wherein the formulation comprises: 1-8% w/w methoprene.