IP Library Granted Patent US 10,085,789
Granted Patent B2
US 10,085,789 · App. 15/457,642 · Granted Oct 2, 2018

Methods and systems for treatment of occipital neuralgia

Inventors: Clint Carnell (Park City, UT); John Allison (Los Altos, CA); Jwala Karnik (Santa Barbara, CA); Jesse Rosen (Redwood City, CA)
Assignee: Myoscience, Inc.
A61B18/0218A61B2018/00041A61B2018/00321A61B2018/00625A61B2018/00839A61B2018/0293
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Quick Facts
Patent No.
US 10,085,789
App. No.
15/457,642
Granted
Oct 2, 2018
Kind
B2
Abstract

A system for alleviating occipital neuralgia. The system has a needle probe having at least one needle. The at least one needle has a proximal end, a distal end, and a needle lumen therebetween, the needle configured for insertion proximate to a location of the occipital nerve. A cooling fluid supply lumen extends distally within the needle lumen to a distal portion of the needle lumen. A cooling fluid source is coupled to the cooling fluid supply lumen to direct cooling fluid flow into the needle lumen. A controller that has at least one processor configured implements an occipital neuralgia treatment algorithm for controlling the cooling fluid source so that liquid from the cooling flow vaporizes within the needle lumen to provide a treatment phase to location of the occipital nerve such that the occipital neuralgia is mitigated.

Claims (16)

1. A method for alleviating pain associated with occipital neuralgia, the method comprising:

positioning a distal end of a cryogenic cooling needle probe proximate to a location of an occipital nerve, the needle probe comprising a pair of needles, each of the needles having a lumen, and wherein the pair of needles are spaced apart to flank at least a portion of the occipital nerve;

flanking the at least a portion of the occipital nerve with the pair of needles;

delivering a treatment to a target tissue with the cryogenic cooling needle probe, the treatment comprising a cooling phase where cooling fluid flows into the needle lumens so that liquid from the cooling fluid flow vaporizes within the needle lumens to provide cooling to the occipital nerve such that the occipital neuralgia is mitigated.

2. The method of claim 1 , further comprising providing a degree of skin warming throughout the delivery of the treatment.

3. The method of claim 1 , wherein the location of the occipital nerve comprises the greater occipital nerve (GON).

4. The method of claim 3 , wherein the pair of needles are spaced apart 3-7 mm to flank the GON, each needle being greater than 6 mm in length.

5. The method of claim 1 , wherein the location of the occipital nerve comprises the lower occipital nerve (LON).

6. The method of claim 5 , wherein the pair of needles are spaced apart 3-7 mm to flank the LON, each needle being greater than 6 mm in length.

7. The method of claim 1 , wherein one or more of: transcutaneous electrical nerve stimulation, percutaneous electrical nerve stimulation, or ultrasound is used to locate the occipital nerve.

8. The method of claim 1 , wherein during the cooling phase the needle probe generates a cryozone having a volume of 65-125 mm 3 .

9. The method of claim 1 , wherein during the cooling phase the needle probe generates a cryozone having a cross-sectional area of 14-55 mm 2 .

10. The method of claim 1 , wherein the pair of needles have a length that is greater than 15 mm.

11. The method of claim 1 , wherein the pair of needles have a length in a range of 3 mm to 15 mm.

12. The method of claim 1 , wherein the pair of needles are spaced apart 3-7 mm to flank the portion of the occipital nerve.

13. The method of claim 1 , wherein the pair of needles are spaced apart 5-8 mm to flank the portion of the occipital nerve.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Dec 5, 2025
From: JPMORGAN CHASE BANK, N.A.
To: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
Reel/Frame 073779/0532 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Mar 31, 2023
From: JPMORGAN CHASE BANK, N.A.
To: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
Reel/Frame 063213/0864 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Mar 31, 2023
From: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 063214/0108 →
SUPPLEMENTAL CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Dec 14, 2021
From: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; FLEXION THERAPEUTICS, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 058516/0636 →
CONFIRMATORY ASSIGNMENT Recorded Jul 15, 2019
From: MYOSCIENCE, INC.
To: PACIRA CRYOTECH, INC.
Reel/Frame 049758/0028 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2017
From: CARNELL, CLINT; ALLISON, JOHN; KARNIK, JWALA; ROSEN, JESSE
To: MYOSCIENCE, INC.
Reel/Frame 044174/0959 →
Continuity (3)
Division 14218901 · Mar 18, 2014
Provisional Application 61800478 · Mar 15, 2013
Related Publication 20170258510A1 · Sep 14, 2017
Cited By (5)
US 12,458,424 US 12,458,530 US 12,521,161 US 12,551,258 US 12,708,422