IP Library Granted Patent US 10,525,080
Granted Patent B2
US 10,525,080 · App. 15/463,992 · Granted Jan 7, 2020

Increasing the half-life of hydrogen peroxide in an ingestible composition

Inventors: Alexander L Huang (Menlo Park, CA); Gin Wu (San Rafael, CA)
Assignee: LIVELEAF, INC.
A61K33/40A01N59/00A61K31/05A61K36/00A61K36/185A61K36/82A01N2300/00
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Quick Facts
Patent No.
US 10,525,080
App. No.
15/463,992
Granted
Jan 7, 2020
Kind
B2
Abstract

The present invention is directed to a method and a composition for producing and using a plant-based biocidal solution. The plant-based biocidal solution contains a bioactive material and a plant-based substance formed from the cellular material of a plant. The plant-based substance is capable of binding to the bioactive material. In some embodiments, the bioactive material is hydrogen peroxide. The hydrogen peroxide can be added exogenously or generated endogenously. In accordance with further embodiments, the plant-based biocidal solution can be applied to a target, thereby impairing the target. In some embodiments, the target can be a pathogen. In accordance with another embodiment, the plant-based substance of the plant-based biocidal solution can form a microscopic duster, a complex, or an aggregate for providing sufficient bioactive material to overcome the defense mechanism of the target.

Claims (11)

1. A method of increasing the half-life of hydrogen peroxide in an ingestible composition, the method comprising:

obtaining an ingestible, water-soluble polyphenol as an extract from a plant, wherein the extract has been heated to substantially inactivate hydrogen peroxide degrading enzymes;

adding hydrogen peroxide to the extract to create the ingestible composition in which the extract is bound to the hydrogen peroxide in the combination; and,

keeping the hydrogen peroxide combined with the extract for gastrointestinal administration;

wherein, the ingestible, water-soluble polyphenol increases the half-life of the hydrogen peroxide in the ingestible composition, wherein the stability of the hydrogen peroxide in the combination is greater in an aqueous solution than the stability of the hydrogen peroxide alone in the aqueous solution.

2. The method of claim 1 , wherein the composition comprises 1% of hydrogen peroxide.

3. The method of claim 1 , wherein the composition comprises 0.05% to 3% of hydrogen peroxide.

4. The method of claim 1 , wherein the composition comprises 0.02% of hydrogen peroxide.

5. The method of claim 1 , wherein the composition is provided in a solid form, the solid form being more compact and stable than an aqueous solution of the extract and the hydrogen peroxide.

6. The method of claim 1 , wherein the combination of the polyphenol and hydrogen peroxide is a biocide.

7. The method of claim 1 , wherein the combination of the polyphenol and hydrogen peroxide is a mycocide.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2022
From: LIVELEAF, INC.
To: LIVELEAF HOLDINGS LLC.
Reel/Frame 061506/0296 →
CHANGE OF ADDRESS Recorded Oct 20, 2022
From: LIVELEAF, INC.
To: LIVELEAF, INC.
Reel/Frame 061733/0245 →
Continuity (5)
Continuation 14221500 · Mar 21, 2014
Continuation 12868634 · Aug 25, 2010
Continuation 12317638 · Dec 23, 2008
Provisional Application 61009484 · Dec 28, 2007
Related Publication 20180036342A1 · Feb 8, 2018