IP Library Granted Patent US 11,085,943
Granted Patent B2
US 11,085,943 · App. 15/465,658 · Granted Aug 10, 2021

High-throughput sample processing systems and methods of use

Inventors: Kyle Allen Lapham (San Francisco, CA); James Frederick Cregg (San Francisco, CA); Daniel Delubac (Los Altos, CA); Stuart Ira Glaser (San Francisco, CA)
G01N35/1074B01L3/021B01L3/5025B01L3/527C12Q1/6806G01N1/38G01N35/00732G01N35/028G01N35/1002G01N35/1004G01N35/1016B01L7/00B01L13/02B01L2200/082B01L2200/143B01L2300/021B01L2300/0627B01L2300/0829B01L2400/0487G01N2035/00356G01N2035/00376G01N2035/00396G01N2035/00752G01N2035/1025G01N2035/1034
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Quick Facts
Patent No.
US 11,085,943
App. No.
15/465,658
Granted
Aug 10, 2021
Kind
B2
Abstract

Disclosed herein are high-throughput sample processing systems and waste management systems, and methods of using the same.

Claims (24)

1. A waste management system for processing waste produced by a high-throughput sample processing system, comprising:

a first pump;

a second pump;

a first valve;

a second valve;

a third valve;

a fourth valve;

a controller communicatively coupled to the high-throughput waste management system and programmed to control the first pump, the second pump, the first valve, the second valve, the third valve and the fourth valve;

a first container fluidly connected to the first pump via the first and second valves, wherein first liquid waste moves from a first liquid waste source to the first container via a suction force provided by the first pump when the controller opens the first and second valves;

a second container fluidly connected to the first pump via the first, second, and third valves, wherein second liquid waste moves from a second liquid waste source to the second container via gravity, and wherein the second liquid waste moves from the second container to the first container via the suction force provided by the first pump when the controller opens the first, second, and third valves;

a third container that holds a sterilizing fluid and is fluidly connected to the first container via the fourth valve;

wherein the second pump pumps the sterilizing fluid into the first container when the controller opens the fourth valve, and

wherein the first container is configured to treat the liquid waste therein with the sterilizing fluid, and to incubate the treated liquid waste in the sterilizing fluid for a predetermined period of time before disposing of the treated liquid waste when directed by the controller.

2. The waste management system of claim 1 , further comprising:

a sample processing plate comprising a plurality of sample wells; and

a plurality of fluid aspirators connected to the first pump and operable to draw the first liquid waste into the first container from the sample wells.

3. The waste management system of claim 1 , further comprising:

a scale operable to measure at least one of the first and second liquid wastes.

4. The waste management system of claim 1 , further comprising:

a fourth container connected to the first and second containers and operable to receive overflow liquid waste from at least one of the first and second containers.

5. The waste management system of claim 1 , further comprising:

a third pump operable to pump the first and second treated liquid wastes into a drainage system.

6. The waste management system of claim 1 , further comprising:

a control system operable to determine an amount of the sterilizing fluid that is to be pumped into the first and second containers.

Assignments (9)
SECURITY INTEREST Recorded Aug 1, 2025
From: MYRIAD GENETICS, INC.; MYRIAD GENETIC LABORATORIES, INC.; MYRIAD WOMEN’S HEALTH, INC.; ASSUREX HEALTH, INC.; GATEWAY GENOMICS, LLC
To: ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP, AS ADMINISTRATIVE AGENT FOR SECURED PARTIES
Reel/Frame 072309/0932 →
RELEASE OF SECURITY INTEREST IN PATENTS PREVIOUSLY RECORDED AT REEL/FRAME (064235/0032) Recorded Aug 1, 2025
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: MYRIAD GENETICS, INC.; MYRIAD WOMEN’S HEALTH, INC.; GATEWAY GENOMICS, LLC; ASSUREX HEALTH, INC.
Reel/Frame 072331/0215 →
RELEASE OF SECURITY INTEREST Recorded Jul 10, 2023
From: JPMORGAN CHASE BANK, N.A.
To: MYRIAD GENETICS, INC.; CRESCENDO BIOSCENCE, INC.; MYRIAD RBM, INC.; MYRIAD WOMEN'S HEALTH, INC.
Reel/Frame 064239/0091 →
PATENT SECURITY AGREEMENT Recorded Jul 7, 2023
From: MYRIAD GENETICS, INC.; MYRIAD WOMEN'S HEALTH, INC.; GATEWAY GENOMICS, LLC; ASSUREX HEALTH, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 064235/0032 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: LAPHAM, KYLE ALLEN; CREGG, JAMES FREDERICK; DELUBAC, DANIEL; GLASER, STUART IRA
To: COUNSYL, INC.
Reel/Frame 064107/0437 →
SECURITY INTEREST Recorded Sep 15, 2020
From: MYRIAD WOMEN'S HEALTH, INC.
To: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
Reel/Frame 053773/0968 →
CHANGE OF NAME Recorded Nov 15, 2018
From: COUNSYL, INC.
To: MYRIAD WOMEN'S HEALTH, INC.
Reel/Frame 047581/0882 →
RELEASE OF SECURITY INTEREST Recorded Jul 31, 2018
From: PERCEPTIVE CREDIT HOLDINGS, LP
To: COUNSYL, INC.
Reel/Frame 046676/0110 →
PATENT SECURITY AGREEMENT Recorded Nov 3, 2017
From: COUNSYL, INC.
To: PERCEPTIVE CREDIT HOLDINGS, LP
Reel/Frame 044364/0851 →