IP Library Granted Patent US 11,232,548
Granted Patent B2
US 11,232,548 · App. 15/466,636 · Granted Jan 25, 2022

System and methods for qualifying medical images

Inventors: Michael D. Abramoff (University Heights, IA); Ben Clark (Cedar Rapids, IA); Eric Talmage (Byron Center, MI); John Casko (Iowa City, IA); Warren Clarida (Cedar Rapids, IA); Meindert Niemeijer (Prairie Village, KS); Timothy Dinolfo (Coralville, IA); Tay Stutts (Iowa City, IA)
Assignee: Digital Diagnostics Inc.
G06T7/0002G16H30/20G16H30/40G06T2207/10101G06T2207/30041G06T2207/30168
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Quick Facts
Patent No.
US 11,232,548
App. No.
15/466,636
Granted
Jan 25, 2022
Kind
B2
Abstract

Disclosed is a system for qualifying medical images submitted by user for diagnostic analysis comprising: an image input module, configured to receive one or more image input by a user; an image protocol conformation module, configured to receive the one or more images from the image input module, and further configured to analyze each of the one or more images for conformity with a predefined protocol and wherein images that do not conform to the predefined protocol are flagged as non-conforming images; an image output module, configured to identify to the user each of the one or more images flagged as non-conforming and prompting the user to resubmit a new image for each of the non-conforming images; and an image resubmission module, configured to receive the user resubmitted image and provide the resubmitted image to the image protocol conformation module.

Claims (31)

1. A system for qualifying medical images submitted by a user for diagnostic analysis comprising:

a non-transitory computer-readable medium comprising memory with instructions encoded thereon; and

one or more processors configured to, when executing the instructions, perform operations comprising:

receiving a plurality of retinal images input by a user, each of the plurality of retinal images capturing a different portion of a retina, wherein the different portions of a retina captured in the plurality of retinal images comprise an optic disk and a fovea, each different portion of a retina corresponding to a respective predefined protocol, wherein the respective protocol corresponding to the optic disk comprises having the optic disk at a center of a field of the respective retinal image, and wherein the respective protocol corresponding to the fovea comprises having the fovea at a center of a field of the respective retinal image;

analyzing each respective one of the plurality of retinal images for conformity with the respective predefined protocol corresponding to the captured portion of the retina in the respective retinal image, and flagging a retinal image that does not conform to its respective predefined protocol as a non-conforming image, the retinal image flagged based on either the optic disk not being at a center of a field of a respective retinal image or the fovea not being at a center of a field of a respective retinal image;

generating for display a graphical interface to the user, the graphical interface comprising each of the plurality of retinal images that were not flagged as non-conforming, and excluding the non-conforming image, wherein the graphical interface includes a placeholder cell for resubmitting a new image of the portion of the retina captured by the non-conforming image;

receiving the user resubmitted image; and

replacing the placeholder cell with the resubmitted image responsive to determining that the resubmitted image conforms to the respective predefined protocol corresponding to the captured portion of the retina.

2. The system of claim 1 , wherein each respective predefined protocol is comprised of one or more image parameters and wherein protocol conformation is established when its respective retinal image conforms with each of the one or more parameters.

3. The system of claim 1 , wherein each retinal image is at least one of a fundus camera image or an optical coherence tomography (OCT) image.

4. The system of claim 3 , wherein each respective protocol comprises one or more retinal image parameters including image quality, field size, and/or retinal coverage.

5. The system of claim 1 , wherein the operations further comprise guiding the user in selecting or generating the user resubmitted image that corrects the non-conformity of the non-conforming image.

6. The system of claim 5 , wherein the system is configured to perform the guiding iteratively through multiple candidate replacement images.

7. The system of claim 1 , wherein analyzing each respective one of the plurality of retinal images for conformity with its respective predefined protocol comprises implementing machine learning from example protocols.

8. The system of claim 1 , wherein analyzing each respective one of the plurality of retinal images for conformity with its respective predefined protocol comprises utilizing rule based heuristics.

9. The system of claim 1 , further comprising a graphic user interface.

10. The system of claim 1 , wherein the one or more processors are at least partially housed in a server.

11. A method for qualifying medical images submitted by a user for diagnostic analysis, the method comprising:

receiving a plurality of retinal images input by a user, each of the plurality of retinal images capturing a different portion of a retina, wherein the different portions of a retina captured in the plurality of retinal images comprise an optic disk and a fovea, each different portion of a retina corresponding to a respective predefined protocol, wherein the respective protocol corresponding to the optic disk comprises having the optic disk at a center of a field of the respective retinal image, and wherein the respective protocol corresponding to the fovea comprises having the fovea at a center of a field of the respective retinal image;

analyzing each respective one of the plurality of retinal images for conformity with the respective predefined protocol corresponding to the captured portion of the retina in the respective retinal image, and flagging a retinal image that does not conform to its respective predefined protocol as a non-conforming image, the retinal image flagged based on either the optic disk not being at a center of a field of a respective retinal image or the fovea not being at a center of a field of a respective retinal image;

generating for display a graphical interface to the user, the graphical interface comprising each of the plurality of retinal images that were not flagged as non-conforming, and excluding the non-conforming image, wherein the graphical interface includes a placeholder cell for resubmitting a new image of the portion of the retina captured by the non-conforming image;

receiving the user resubmitted image; and

replacing the placeholder cell with the resubmitted image responsive to determining that the resubmitted image conforms to the respective predefined protocol corresponding to the captured portion of the retina.

12. The method of claim 11 , wherein each respective predefined protocol is comprised of one or more image parameters and wherein protocol conformation is established when its respective retinal image conforms with each of the one or more parameters.

13. The method of claim 11 , wherein each retinal image is at least one of a fundus camera image or an optical coherence tomography (OCT) image.

14. A non-transitory computer-readable medium comprising memory with instructions encoded thereon for qualifying medical images submitted by a user for diagnostic analysis, the instructions causing one or more processors to perform operations when executed, the instructions comprising instructions to:

receive a plurality of retinal images input by a user, each of the plurality of retinal images capturing a different portion of a retina, wherein the different portions of a retina captured in the plurality of retinal images comprise an optic disk and a fovea, each different portion of a retina corresponding to a respective predefined protocol, wherein the respective protocol corresponding to the optic disk comprises having the optic disk at a center of a field of the respective retinal image, and wherein the respective protocol corresponding to the fovea comprises having the fovea at a center of a field of the respective retinal image;

analyze each respective one of the plurality of retinal images for conformity with the respective predefined protocol corresponding to the captured portion of the retina in the respective retinal image, and flagging a retinal image that does not conform to its respective predefined protocol as a non-conforming image, the retinal image flagged based on either the optic disk not being at a center of a field of a respective retinal image or the fovea not being at a center of a field of a respective retinal image;

generate for display a graphical interface to the user, the graphical interface comprising each of the plurality of retinal images that were not flagged as non-conforming, and excluding the non-conforming image, wherein the graphical interface includes a placeholder cell for resubmitting a new image of the portion of the retina captured by the non-conforming image;

receive the user resubmitted image; and

replace the placeholder cell with the resubmitted image responsive to determining that the resubmitted image conforms to the respective predefined protocol corresponding to the captured portion of the retina.

Assignments (3)
CHANGE OF NAME Recorded Jun 23, 2020
From: IDX TECHNOLOGIES INC.
To: DIGITAL DIAGNOSTICS INC.
Reel/Frame 053020/0199 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 17, 2019
From: IDX, L.L.C.
To: IDX TECHNOLOGIES INC.
Reel/Frame 050754/0736 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 16, 2017
From: ABRAMOFF, MICHAEL D; CLARK, BEN; TALMAGE, ERIC; CASKO, JOHN; CLARIDA, WARREN; NIEMEIJER, MEINDERT; DINOLFO, TIMOTHY; STUTTS, TAY
To: IDX, LLC
Reel/Frame 042388/0246 →
Continuity (2)
Provisional Application 62311660 · Mar 22, 2016
Related Publication 20170278241A1 · Sep 28, 2017