(1-AZINONE)-SUBSTITUTED PYRIDOINDOLES

1 . A compound of formula I:

wherein

R 1 is H or optionally substituted alkyl;

R 2 , R 3 , R 4 are each independently selected from H, —O-alkyl, —S-alkyl, alkyl, halo, —CF 3 , and —CN;

G is —CR 12 R 13 —NR 5 — or —NR 5 —CR 12 R 13 ;

R 5 is H, optionally substituted alkyl, optionally substituted heterocycle, —C(═O)—R 6 , —C(═O)—O—R 7 , or —C(═O)—NR 19 R 20 ;

R 6 and R 7 are each optionally substituted alkyl or optionally substituted heterocycle;

R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 19 and R 20 are each independently selected from H or optionally substituted alkyl;

R 14 and R 15 are each independently H or halogen;

Y is N;

L is —CH 2 —O—, —CH 2 CH 2 —, —CH═CH— or a bond; and

B is aryl or heteroaryl or cycloalkyl;

with the proviso that, when L is a direct bond, B cannot be unsubstituted heteroaryl or heteroaryl monosubstituted with fluorine.

2 . A method of treating a disease or condition which is susceptible to treatment with an MCH 1 receptor modulator, comprising administering to a patient in need thereof a therapeutically effective amount of a compound according to claim 1 .