IP Library › Granted Patent US 10,016,403
Granted Patent B2
US 10,016,403 · App. 15/478,430 · Granted Jul 10, 2018

Sublingual fentanyl spray

Inventors: S. George Kottayil (Long Grove, IL); Venkat R. Goskonda (Phoenix, AZ); Zhongyuan Zhu (Vernon Hills, IL); Linet Kattookaran (Mount Prospect, IL); Neha Parikh (Chicago, IL)
Assignee: INSYS DEVELOPMENT COMPANY, INC.
A61K31/4468A61K9/006A61K9/0056A61K31/435A61K31/445A61K47/10A61M11/00
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Quick Facts
Patent No.
US 10,016,403
App. No.
15/478,430
Granted
Jul 10, 2018
Kind
B2
Abstract

The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.

Claims (2)

1. A sublingual formulation comprising from about 0.1% to about 0.9% by weight fentanyl, a free base or a pharmaceutically acceptable salt thereof, or a fentanyl derivative selected from the group consisting of sufentanil, carfentanil, lofentanil and alfentanil, from about 20% to about 60% by weight ethanol and from about 1% to about 30% by weight propylene glycol.

2. The sublingual formulation of claim 1 , wherein the concentration of ethanol is from about 50% to about 60% by weight.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 8, 2019
From: INSYS THERAPEUTICS, INC.; INSYS DEVELOPMENT COMPANY, INC.
To: BTCP PHARMA, LLC
Reel/Frame 050657/0793 →
Continuity (6)
Continuation 15042999 · Feb 12, 2016
Continuation 14448720 · Jul 31, 2014
Continuation 13895124 · May 15, 2013
Continuation 11698739 · Jan 25, 2007
Provisional Application 60762057 · Jan 25, 2006
Related Publication 20170202820A1 · Jul 20, 2017
Cited By (1)
US 12,458,620