IP Library Granted Patent US 10,610,523
Granted Patent B2
US 10,610,523 · App. 15/478,499 · Granted Apr 7, 2020

Sublingual fentanyl spray

Inventors: S. George Kottayil (Long Grove, IL); Venkat R. Goskonda (Phoenix, AZ); Zhongyuan Zhu (Vernon Hills, IL); Linet Kattookaran (Mount Prospect, IL); Neha Parikh (Chicago, IL)
Assignee: BTCP PHARMA, LLC
A61K31/4468A61K9/006A61K9/0053A61K9/0056A61K31/435A61K31/445A61K47/10A61M11/00
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Quick Facts
Patent No.
US 10,610,523
App. No.
15/478,499
Granted
Apr 7, 2020
Kind
B2
Abstract

The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.

Claims (1)

1. A sublingual spray formulation comprising from about 100 to about 800 micrograms of fentanyl, from about 20% to about 60% w/v ethanol and from about 4% to about 6% w/v propylene glycol wherein the formulation provides a mean time to lower limit of quantification (LLOQ) of fentanyl of about 5 minutes when administered to humans, wherein w/v denotes weight by volume.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 8, 2019
From: INSYS THERAPEUTICS, INC.; INSYS DEVELOPMENT COMPANY, INC.
To: BTCP PHARMA, LLC
Reel/Frame 050657/0793 →
Continuity (7)
Continuation 14966301 · Dec 11, 2015
Continuation 14448752 · Jul 31, 2014
Continuation 13895111 · May 15, 2013
Continuation 12221333 · Aug 1, 2008
Provisional Application 60963253 · Aug 3, 2007
Provisional Application 60963076 · Aug 2, 2007
Related Publication 20170239230A1 · Aug 24, 2017