IP Library › Patent Application 15491505
Patent Application
App. No. 15/491,505

METHOD FOR SEQUENCING A HETEROPOLYMERIC TARGET NUCLEIC ACID SEQUENCE

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Quick Facts
Patent No.
US None
App. No.
15/491,505
Abstract

The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore.

Claims (3)

1 . A method for sequencing a heteropolymeric target nucleic acid sequence, comprising:

(a) passing the target sequence through a transmembrane pore so that a proportion of the nucleotides in the target sequence interacts one at a time with at least one site in the pore that is capable of discriminating between different nucleotides; and

(b) measuring the current passing through the pore during each interaction and thereby determining the sequence of the target sequence.