Method for producing substituted anthranilic acid derivatives
The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R 1 , R 2 , R 3 and R 4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).
1. A compound of formula (IV)
where
R 1 is a hetaryl radical of the general formula (II)
where
R 8 is fluorine or chlorine,
Z is N,
and
Y is a radical of the general formula (III)
where
R 9 is CF 3 or C 2 F 5 ,
R 3 is methyl,
R 4 is chlorine or cyano,
and
X is bromine.
2. A compound of formula (IV) according to claim 1 , wherein R 8 is fluorine.
3. A compound of formula (IV) according to claim 1 , wherein R 8 is chlorine.
4. A compound of formula (IV) according to claim 1 , wherein R 9 is CF 3 .
5. A compound of formula (IV) according to claim 1 , wherein R 9 is C 2 F 5 .
6. A compound of formula (IV) according to claim 1 , wherein R 4 is chlorine.
7. A compound of formula (IV) according to claim 1 , wherein R 4 is cyano.