Medical image processing apparatus and medical image diagnostic apparatus

1. A medical image processing apparatus which analyzes blood flow dynamics in a predetermined region of a subject, the blood flow dynamics being generated from medical images obtained by imaging the predetermined region in time sequence over a plurality of time phases, the medical image processing apparatus comprising:

processing circuitry configured to

correct pixel values of a target image after being aligned, according to an amount of deformation of the target image when the target image is aligned with a reference image by executing the program read out from memory circuitry, the reference image and the target image being among the medical images in the plurality of time phases,

set a same grid on each of the reference image and the target image, thereby dividing each of the reference image and the target image into a plurality of regions in a grid-like arrangement,

calculate a relational expression between the deformation rate of the grid and a rate of change of the pixel values, and

correct the medical image based on the relational expression.

2. The medical image processing apparatus according to claim 1 , wherein the processing circuitry is further configured to

calculate a deformation rate of the grid on the target image subjected to the alignment, by comparison with the grid on the reference image, and

multiply pixel values of a target image after being aligned by a reciprocal of the deformation rate of the grid and thereby correcting the pixel values of the target image after being aligned.

3. The medical image processing apparatus according to claim 1 , wherein the processing circuitry is further configured to conduct image analysis based on the corrected medical image using a time density curve, generate an analysis result, and control a display to display the analysis result.

4. The medical image processing apparatus according to claim 2 , wherein the processing circuitry is further configured to conduct image analysis based on the corrected medical image using a time density curve, generate an analysis result, and control a display to display the analysis result.

5. The medical image processing apparatus according to claim 3 , wherein in the target image after being aligned, the processing circuitry determines a region with a high rate of change to be an alert region, generates an alert display by superimposing the alert region on the medical image, and further presents the alert display on the display.

6. The medical image processing apparatus according to claim 4 , wherein in the target image after being aligned, the processing circuitry determines a region with a high rate of change to be an alert region, generates an alert display by superimposing the alert region on the medical image, and further presents the alert display on the display.

7. The medical image processing apparatus according to claim 3 , wherein

the display displays a region of a medical image yet to undergo the alignment and a region of a medical image resulting from the alignment, the regions corresponding to a same region in the medical images, and

based on which of the region before the alignment and the region after the alignment is selected, the processing circuitry controls the display to display an analysis result generated based on the medical image yet to undergo the alignment, followed by an analysis result generated based on a medical image obtained by making a correction after the alignment.

8. The medical image processing apparatus according to claim 4 , wherein

the display displays a region of a medical image yet to undergo the alignment and a region of a medical image resulting from the alignment, the regions corresponding to a same region in the medical images, and

based on which of the region before the alignment and the region after the alignment is selected, the processing circuitry controls the display to display an analysis result generated based on the medical image yet to undergo the alignment, followed by an analysis result generated based on a medical image obtained by making a correction after the alignment.

9. The medical image processing apparatus according to claim 5 , wherein

the display displays a region of a medical image yet to undergo the alignment and a region of a medical image resulting from the alignment, the regions corresponding to a same region in the medical images, and

based on which of the region before the alignment and the region after the alignment is selected, the processing circuitry controls the display to display an analysis result generated based on the medical image yet to undergo the alignment, followed by an analysis result generated based on a medical image obtained by making a correction after the alignment.

10. The medical image processing apparatus according to claim 6 , wherein

the display displays a region of a medical image yet to undergo the alignment and a region of a medical image resulting from the alignment, the regions corresponding to a same region in the medical images, and

based on which of the region before the alignment and the region after the alignment is selected, the processing circuitry controls the display to display an analysis result generated based on the medical image yet to undergo the alignment, followed by an analysis result generated based on a medical image obtained by making a correction after the alignment.

11. The medical image processing apparatus according to claim 3 , wherein the processing circuitry generates a time density curve as an analysis result by performing calculations using a non-linear least squares method which assigns weights based on magnitude of a deformation rate of the grid.

12. The medical image processing apparatus according to claim 11 , wherein the processing circuitry conducts a blood flow dynamics analysis based on the time density curve and displays a result of the blood flow dynamics analysis on the display.

13. The medical image processing apparatus according to claim 1 , wherein the processing circuitry is further configured to

store the relational expression into the memory circuitry, and

correct the medical image based on the relational expression stored in the memory circuitry.

14. The medical image processing apparatus according to claim 1 , wherein the medical images are acquired over the plurality of time phases in a same respiratory cycle after administering a contrast medium to the subject.

15. A medical image diagnostic apparatus, comprising:

a scanner configured to acquire a plurality of medical images by imaging a predetermined region of a subject in time sequence; and

processing circuitry configured to

correct pixel values of a target image according to an amount of deformation of the target image when the target image is aligned with a reference image by executing a program read out from memory circuitry, the reference image and the target image being among the medical images in the plurality of time phases,

set a same grid on each of the reference image and the target image, thereby dividing each of the reference image and the target image into a plurality of regions in a grid-like arrangement,

calculate a relational expression between the deformation rate of the grid and a rate of change of the pixel values, and

correct the medical image based on the relational expression.

16. The medical image processing apparatus according to claim 1 , wherein the processing circuitry compares the target image after being aligned with the reference image, thereby calculating a deformation rate of the target image with respect to the reference image by alignment as the amount of deformation.