Optical sensor, capnography system and methods of use
The present application describes an optical sensor for measuring oxygen gas levels in a medium. The optical sensor includes a substrate having a first and second surface. The optical sensor also includes a first coating applied on the first surface of the substrate. The first coating may include an oxygen impermeable matrix doped with a first fluorophore. The optical sensor may include a second coating applied on the substrate. The present application also describes a capnography system for measuring oxygen including an optical sensor and an algorithm to estimate the maxima of oxygen levels from instantaneous oxygen levels and calculating instantaneous carbon dioxide levels from the difference between average maximum oxygen gas level and instantaneous oxygen gas level.
1. A capnography system for measuring oxygen comprising:
an optical fiber including a proximal end and a distal end;
an optical sensor positioned adjacent to the distal end of the optical fiber, the optical sensor comprising:
a substrate having a first and a second surface opposite the first surface;
a first coating layer applied on the first surface of the substrate, the first coating layer including a first fluorophore having a fluorescence characteristic that is dependent upon temperature; and
a second coating layer applied on the first coating layer or on the second surface of the substrate, the second coating layer including an oxygen permeable matrix and a second fluorophore having a fluorescence characteristic that is dependent upon temperature and oxygen concentration;
an excitation source that transmits light from the proximal end of the optical fiber to the distal end of the optical fiber to excite the first and second fluorophores of the optical sensor; and
a fluorescence emission sensor that receives one or more fluorescence characteristics from each of the first and second fluorophores travelling from the distal end of the optical fiber to the proximal end of the optical fiber.
2. The system of claim 1 , further comprising:
a graphical display operably connected to the emission fluorescence sensor.
3. The system of claim 1 , further comprising:
an audio device operably connected to the emission fluorescence sensor, the audio device including an alarming mechanism sensitive to a signal exceeding a predetermined threshold.
4. The system of claim 1 , further comprising:
a wireless display connected to the fluorescence emission sensor for assessing a signal from a remote location.
5. The system of claim 1 , further comprising an oxygen barrier layer applied between the first coating layer and the second coating layer.
6. The system of claim 1 , wherein the second coating layer includes an oxygen impermeable matrix.
7. The system of claim 1 , wherein the substrate is oxygen impermeable.
8. The system of claim 1 , wherein the oxygen permeable matrix includes polystyrene and the oxygen impermeable matrix includes sol gel.
9. The system of claim 1 , wherein the first and second fluorophores are selected from Ruthenium organic complexes, Platinum organic complexes and combinations thereof.
10. The system of claim 9 , wherein the first fluorophore is a Ruthenium organic complex.
11. The system of claim 9 , wherein the second fluorophore is a platinum organic complex.
12. The system of claim 1 , wherein the fluorescence characteristic is selected from fluorescence intensity, decay rate, lifetime, phase shift and combinations thereof.
13. The system of claim 1 , wherein the substrate includes a material selected from acrylic, quartz, clear plastics and combinations thereof.