IP Library Granted Patent US 11,344,047
Granted Patent B2
US 11,344,047 · App. 15/514,876 · Granted May 31, 2022

Methods and formulations for reducing bovine emissions

Inventors: Cory T. Herr (Greens Fork, IN); John Charles Kube (Greenfield, IN); Jerold Scott Teeter (Greenfield, IN)
Assignee: Elanco US Inc.
A23K20/111A23K10/40A23K20/121A23K20/132A23K20/184A23K20/195A23K50/10A23K10/00A23V2002/00
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Quick Facts
Patent No.
US 11,344,047
App. No.
15/514,876
Granted
May 31, 2022
Kind
B2
Abstract

The present disclosure provides methods and formulations for reducing ammonia and carbon dioxide emissions from a bovine using lubabegron, or a physiologically acceptable salt thereof. The present disclosure also provides bovine feed additives and bovine feed compositions.

Claims (20)

1. A method of reducing ammonia emissions from a bovine in need thereof comprising orally administering to said bovine lubabegron, or a physiologically acceptable salt thereof.

2. The method of claim 1 , wherein lubabegron, or a physiologically acceptable salt thereof, is the hemifumarate salt thereof.

3. The method of claim 1 , wherein said lubabegron, or a physiologically acceptable salt thereof, is administered in an animal feed.

4. The method of claim 1 , wherein one or more other active ingredients are administered to said bovine, wherein said other active ingredients are one or more selected from the group consisting of monensin, tylosin, and melengestrol, or physiologically acceptable salts thereof.

5. The method of claim 1 , wherein said bovine is a cow.

6. The method of claim 1 , wherein said reduction is per pound of live weight of said bovine.

7. The method of claim 1 , wherein said reduction is per pound of hot carcass weight of said bovine.

8. A method for reduction of ammonia gas emissions per pound of live weight and hot carcass weight in beef steers and heifers, the method comprising feeding said beef steers and heifers in confinement for slaughter during the last 14 to 91 days a feed comprising lubabegron or a physiologically acceptable salt thereof.

9. A method of reducing carbon dioxide emissions from a bovine in need thereof comprising orally administering to said bovine lubabegron, or a physiologically acceptable salt thereof.

10. The method of claim 9 , wherein lubabegron, or a physiologically acceptable salt thereof, is the hemifumarate salt thereof.

11. The method of claim 9 , wherein said lubabegron, or a physiologically acceptable salt thereof, is administered in an animal feed.

12. The method of claim 9 , wherein one or more other active ingredients are administered to said bovine, wherein said other active ingredients are one or more selected from the group consisting of monensin, tylosin, and melengestrol, or physiologically acceptable salts thereof.

13. The method of claim 9 , wherein said bovine is a cow.

14. The method of claim 9 , wherein said reduction is per pound of live weight of said bovine.

15. The method of claim 9 , wherein said reduction is per pound of hot carcass weight of said bovine.

16. The method of claim 1 , comprising administering an additional ingredient to said bovine, wherein said additional ingredient is monensin or a physiologically acceptable salt thereof.

17. The method of claim 1 , comprising administering additional ingredients to said bovine, wherein said additional ingredients are monensin or a physiologically acceptable salt thereof, and tylosin or a physiologically acceptable salt thereof.

18. The method of claim 8 , wherein lubabegron, or a physiologically acceptable salt thereof, is the hemifumarate salt thereof.

19. The method of claim 16 , wherein lubabegron, or a physiologically acceptable salt thereof, is the hemifumarate salt thereof.

20. The method of claim 17 , wherein lubabegron, or a physiologically acceptable salt thereof, is the hemifumarate salt thereof.

Assignments (4)
ASSIGNMENT OF SECURITY INTEREST IN PATENT RIGHTS, RECORDED ON AUGUST 3, 2020, AT REEL/FRAME 053388/0967 Recorded Dec 3, 2025
From: GOLDMAN SACHS BANK USA, AS RETIRING COLLATERAL AGENT
To: JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT
Reel/Frame 073816/0021 →
SECURITY INTEREST Recorded Aug 3, 2020
From: ELANCO US INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 053388/0967 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 23, 2018
From: ELI LILLY AND COMPANY
To: ELANCO US INC.
Reel/Frame 044703/0440 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2017
From: HERR, CORY T.; KUBE, JOHN CHARLES; TEETER, JEROLD SCOTT
To: ELI LILLY AND COMPANY
Reel/Frame 041765/0026 →