Photoactivatable fibers and fabric media
In various aspects, the present disclosure relates to fibers and fabric media comprising photoactivatable agents and to fibers and fabric media that are photoactivatable by photoactivation of the photoactivatable agents. In some instances, the fibers and the fabric media have photoactivatable agents present on their surface (e.g., the fiber/fabric is coated or sprayed with the photoactivatable agents or the fiber/fabric is dipped into a composition or a formulation comprising the photoactivatable agent). In other instances, the photoactivatable agents are incorporated into the materials making the fibers (e.g., the photoactivatable agents are mixed/compounded with the materials making the fibers). The photoactivatable fibers of the present disclosure comprise at least one thermoplastic polymer and at least photoactivatable agent that absorbs and emits light between about 400 nm and about 800 nm.
1. A photoactivatable fiber, wherein the photoactivatable fiber comprises:
at least one thermoplastic polymer selected from one or more of acrylonitrile butadiene styrene (ABS), polyether sulfone (PES), polyetherether ketone (PEEK), polyphenylene oxide (PPO), polybutylene, polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate polyester, and poly(methyl methacrylate) (PMMA), and
at least one xanthene dye;
wherein the at least one xanthene dye is compounded and extruded with the at least one thermoplastic polymer;
wherein the at least one xanthene dye is present in the at least one thermoplastic polymer at a concentration of between about 10 g/L and about 100 g/L of the total volume of the at least one thermoplastic polymer; and
wherein the photoactivatable fiber is responsive to actinic light to emit fluorescent light having a power density of between about 0.005 mW/cm 2 to about 8 mW/cm 2 .
2. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is uniformly dispersed throughout the photoactivatable fiber.
3. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is non-uniformly dispersed throughout the photoactivatable fiber.
4. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is layered on the surface of the photoactivatable fiber.
5. The photoactivatable fiber as defined in claim 4 , wherein the photoactivatable fiber comprises at least one layer of the at least one xanthene dye on its surface.
6. The photoactivatable fiber as defined in claim 4 , wherein the photoactivatable fiber comprises more than one layer of the at least one xanthene dye on its surface.
7. The photoactivatable fiber as defined in claim 1 , wherein the at least one thermoplastic polymer is one or more of polybutylene terephthalate (PBT), and poly(methyl methacrylate) (PMMA).
8. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is selected from the group consisting of Eosin Y, Eosin B, Erythrosine, Fluorescein, Rose Bengal and any mixture thereof.
9. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is Eosin Y.
10. The photoactivatable fiber as defined in claim 1 , wherein the at least one xanthene dye is responsive to actinic light to emit light having a wavelength of between about 400 nm and about 800 nm.
11. The photoactivatable fiber as defined in claim 1 , the photoactivatable fiber having a linear mass density of between 400 Deniers and 480 Deniers.
12. The photoactivatable fiber as defined in claim 1 , further comprising a lubricant.
13. A photoactivatable fabric comprising a plurality of photoactivatable fibers wherein the photoactivatable fibers comprise:
i) at least one thermoplastic polymer selected from one or more of acrylonitrile butadiene styrene (ABS), polyether sulfone (PES), polyetherether ketone (PEEK), polyphenylene oxide (PPO), polybutylene, polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate polyester, and poly(methyl methacrylate) (PMMA), and
ii) at least one xanthene dye, wherein the at least one xanthene dye is compounded and extruded into the photoactivatable fibers;
wherein the at least one xanthene dye is present in the at least one thermoplastic polymer at a concentration of between about 10 g/L and about 100 g/L of the total volume of the at least one thermoplastic polymer; and
wherein the photoactivatable fibers are responsive to actinic light to emit fluorescent light having a power density of between about 0.005 mW/cm 2 to about 8 mW/cm 2 .
14. A method for effecting phototherapy on a subject, the method comprising:
applying a photoactivatable fiber onto the subject, wherein the photoactivatable fiber comprises at least one thermoplastic polymer selected from one or more of acrylonitrile butadiene styrene (ABS), polyether sulfone (PES), polyetherether ketone (PEEK), polyphenylene oxide (PPO), polybutylene, polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate polyester, and poly(methyl methacrylate) (PMMA), and at least one xanthene dye; wherein the at least one xanthene dye is compounded and extruded with the at least one thermoplastic polymer;
wherein the at least one xanthene dye is present in the at least one thermoplastic polymer at a concentration of between about 10 g/L and about 100 g/L of the total volume of the at least one thermoplastic polymer; and
illuminating the photoactivatable fiber; wherein illumination of the photoactivatable fiber causes the photoactivatable fiber to emit fluorescent light having a power density of between about 0.005 mW/cm 2 to about 8 mW/cm 2 .