Compositions comprising a compound from the family of avermectins and an agonist compound for at least one of the retinoic acid receptors for treating acne
View Patent ↗Compositions including a compound of the family of avermectins, preferably ivermectin, and an agonist compound for at least one of the retinoic acid receptors are described. The compositions are in particular used in the treatment of acne.
1. A topical composition, consisting of:
(a) 0.1% to 2% by weight, relative to the total weight of the composition, of ivermectin;
(b) 0.001% to 1% by weight, relative to the total weight of the composition, of trifarotene; and
(c) one or more pharmaceutically acceptable excipients.
2. The composition according to claim 1 , wherein the ivermectin is present in an amount of 1% by weight, relative to the total weight of the composition, and the trifarotene is present in an amount from 0.005% to 1% by weight, relative to the total weight of the composition.
3. The composition according to claim 1 , wherein the composition is formulated for topical administration.
4. The composition according to claim 1 , wherein the composition is in the form of a gel, a lotion or a cream.
5. The composition according to claim 1 , wherein the ivermectin is present in an amount of 1% by weight, relative to the total weight of the composition.
6. The composition according to claim 1 , wherein the trifarotene is present in an amount of 0.005% by weight, relative to the total weight of the composition.