Neuromodulation device
The invention provides devices and methods that can prevent or ameliorate bronchoconstriction. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve or the pulmonary branches of the vagus nerves. The signal is able to treat bronchoconstriction and prevent and/or ameliorate bronchoconstriction.
1. An apparatus for inhibiting the neural activity of a vagal nerve of a patient, the apparatus comprising:
one or more transducers each configured to apply a signal to a vagal nerve of the patient; and
a controller coupled to the one or more transducers, the controller controlling the signal to be applied by each of the one or more transducers, so that the signal inhibits the neural activity of the vagal nerve to reduce parasympathetic tone response in the patient;
wherein, upon cessation of the signal application, the modulation in neural activity remains substantially the same as when the signal was being applied by the one or more transducers, and wherein the modulation in neural activity as a result of the one or more transducers applying the signal is substantially persistent.