METHODS FOR FORMULATING ORALLY INGESTIBLE COMPOSITIONS COMPRISING LIPOPHILIC ACTIVE AGENTS
Aspects described herein relate to improved methods for infusing food and beverage compositions with lipophilic active agents. More particularly, aspects described herein relate to improved methods for infusing food and beverage compositions with lipophilic active agents using tapioca starch or related compounds. Lipophilic active agents include cannabinoids, nicotine, nonsteroidal anti-inflammatories (NSAIDs), and vitamins.
1 - 21 . (canceled)
22 . A cannabinoid infused food product comprising:
(a) a therapeutically effective amount of the cannabinoid;
(b) a bioavailability enhancing agent, wherein the bioavailability enhancing agent enhances the bioavailability of the cannabinoid;
(c) a starch, wherein the starch is selected from the group consisting of tapioca starch, corn starch, potato starch, gelatin, dextrin, cyclodextrin, oxidized starch, starch ester, starch ether, crosslinked starch, alpha starch, octenylsuccinate ester, and processed starch obtained by treating a starch by an acid, heat, or enzyme; and
(d) a food product, wherein the food product is selected from the group consisting of tea leaves, coffee beans, cocoa powder, meats, fish, fruits, vegetables, dairy products, legumes, pastas, breads, grains, seeds, nuts, spices, and herbs.
23 . The cannabinoid infused food product of claim 22 obtainable by the steps of:
(i) contacting the food product with an oil comprising the cannabinoid and the bioavailability enhancing agent; and
(ii) dehydrating the food product, wherein dehydrating comprises contacting the food product with the starch;
thereby producing the cannabinoid infused food product.
24 . The cannabinoid infused food product of claim 23 , wherein step (i) comprises saturating the food product in the oil comprising the cannabinoid and the bioavailability enhancing agent.
25 . The cannabinoid infused food product of claim 23 , wherein the bioavailability enhancing agent is a protective colloid, an edible oil or fat, and a cannabinoid taste masking agent.
26 . The cannabinoid infused food product of claim 25 , wherein the bioavailability enhancing agent that is a protective colloid, an edible oil or fat, and a cannabinoid taste masking agent is nonfat dry milk.
27 . The cannabinoid infused food product of claim 26 , wherein the bioavailability enhancing agent is substantially free of omega-6 fatty acids.
28 . The cannabinoid infused food product of claim 23 , wherein the bioavailability of the cannabinoid in a subject is at least about 1.5 times greater than the bioavailability of the cannabinoid in the subject in the absence of the bioavailability enhancing agent.
29 . The cannabinoid infused food product of claim 23 , wherein the bioavailability of the cannabinoid in a subject is greater than 20%.
30 . The cannabinoid infused food product of claim 23 , further wherein the cannabinoid infused food product is lyophilized.
31 . The cannabinoid infused food product of claim 23 , wherein the cannabinoid is a nonpsychoactive cannabinoid.
32 . The cannabinoid infused food product of claim 23 , wherein the cannabinoid is a psychoactive cannabinoid.
33 . A cannabinoid infused beverage product obtainable by the steps of:
(i) providing cannabinoid infused tea leaves, coffee beans, or cocoa powder according to claim 23 ; and
(ii) steeping the cannabinoid infused tea leaves, coffee beans, or cocoa powder in a liquid;
thereby producing the cannabinoid infused beverage product.
34 . The cannabinoid infused beverage product of claim 33 , wherein the bioavailability enhancing agent is a protective colloid, an edible oil or fat, and a cannabinoid taste masking agent.
35 . The cannabinoid infused beverage product of claim 34 , wherein the bioavailability enhancing agent that is a protective colloid, an edible oil or fat, and a cannabinoid taste masking agent is nonfat dry milk.
36 . The cannabinoid infused beverage product of claim 35 , wherein the bioavailability enhancing agent is substantially free of omega-6 fatty acids.
37 . The cannabinoid infused beverage product of claim 33 , wherein the bioavailability of the cannabinoid in a subject is at least about 1.5 times greater than the bioavailability of the cannabinoid in the subject in the absence of the bioavailability enhancing agent.
38 . The cannabinoid infused beverage product of claim 33 , wherein the bioavailability of the cannabinoid in a subject is greater than 20%.
39 . The cannabinoid infused beverage product of claim 33 , wherein the cannabinoid is a nonpsychoactive cannabinoid.
40 . The cannabinoid infused beverage product of claim 33 , wherein the cannabinoid is a psychoactive cannabinoid.