IP Library Granted Patent US 10,420,491
Granted Patent B2
US 10,420,491 · App. 15/576,671 · Granted Sep 24, 2019

Device and method for generating calibration factors for use in determining biological indicator levels in tissue

Inventors: Nithin O. Rajan (Austin, TX); Dustin M. Freckleton (Austin, TX); Paulo E. Xavier da Silveira (Boulder, CO); Byron Olson (Boone, IA)
Assignee: LVL Technologies, Inc.
A61B5/14551A61B5/0075A61B5/0205A61B5/02007A61B5/02438A61B5/0402A61B5/1455A61B5/1495A61B5/14532A61B5/14535A61B5/14546A61B5/4875A61B5/6828A61B5/02416
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Quick Facts
Patent No.
US 10,420,491
App. No.
15/576,671
Granted
Sep 24, 2019
Kind
B2
Abstract

Optical-electronic device configured to generate a calibration factor for use in determining optical density. The device includes at least one emitter configured to emit light, a detector configured to receive light and transmit data representative of the received light and a processor coupled to the at least one emitter and the detector. The device further includes a non-transitory storage medium coupled to the processor and configured to store instruction to cause the device to perform the calibration method. Additionally, a calibration container includes a main body, upper lid, and a lower lid. The main body is configured to receive the device and an object having known optical properties.

Claims (48)

1. A device configured to generate at least one calibration factor for use in determining optical density, the device comprising:

a plurality of emitters, each having at least one light source, each of the emitters configured to emit light;

a detector configured to receive light and transmit data representative of the received light;

at least two of the plurality of emitters are spaced at different distances from the detector;

a processor coupled to the at least one emitter and the detector;

a non-transitory storage medium coupled to the processor and configured to store instructions to cause the device to repeat the following for each of the light sources:

emit light from one of the light sources of one of the emitters at a predetermined current towards an object that has a known optical density;

detect, at the detector, a portion of the emitted light corresponding to the predetermined current;

calculate, at the processor, a corresponding calibration factor based on the detected portion of emitted light through the object;

store the corresponding calibration factor in the non-transitory storage medium.

2. The device as recited in claim 1 , further comprising instructions to cause, repeatedly for each light source and each of a plurality of predetermined currents, the device to:

emit light from one of the at least one light source of the at least one emitter at one of the plurality of predetermined currents towards the object;

detect, at the detector, a portion of the emitted light corresponding to the predetermined current;

calculate, at the processor, a corresponding calibration factor based on the detected portion of emitted light through the object;

store the corresponding calibration factor in the non-transitory storage medium.

3. The device as recited in claim 1 , wherein the at least one emitter comprises a plurality of emitters and each of the plurality of emitters having a plurality of light sources, and further comprising instructions to cause the device to:

emit light, towards the object, from one of the plurality of light sources of one of the emitters at one of a plurality of predetermined currents;

detect, at the detector, a portion of the emitted light corresponding to the one of a the plurality of predetermined currents;

calculate, at the processor, a corresponding calibration factor based on the detected portion of emitted light through the object;

store the corresponding calibration factor in the non-transitory storage medium.

4. The device as recited in claim 1 , wherein the predetermined current comprises a plurality of currents and each of the steps are performed for each of the plurality of currents.

5. The device in claim 4 , further comprising instructions stored on the non-transitory storage medium to cause the device to:

confirm that at least one calibration factor is stored for each light source at the plurality of currents.

6. The device as recited in claim 5 , wherein the plurality of predetermined currents are based on a corresponding plurality of predetermined currents and the calculation of the corresponding calibration factor is derived using the formula: C ijm =10 ODjm /D ijm , where i is an index tracking a predetermined current value, j is an index tracking a light source, m is an index tracking a spacing between the light source and detector, OD is the optical density, and D is measured light data.

7. The device as recited in claim 5 , wherein the non-transitory storage medium further comprises instructions, upon receiving a measurement command, to:

emitting, iteratively, light from one of a plurality of light sources at one of a plurality of predetermined currents towards the object;

detecting, at a detector, a portion of the emitted light corresponding to a respective one of the light sources and predetermined currents;

determining an optical density of the object based on the calibration factors.

8. The device as recited in claim 1 , wherein the corresponding calibration factor is transmitted via a network interface component to a server.

9. The device as recited in claim 1 , wherein the corresponding calibration factor is transmitted via a network interface component to an external electronic device.

10. The device as recited in claim 1 , wherein the object is made of a material that is designed to mimic a biological tissue.

11. The device as recited in claim 1 , wherein the at least one emitter comprises at least two emitters that are spaced apart from each other and from the detector.

12. The device as recited in claim 11 , wherein one of the emitters is further away from the detector than the other.

13. The device as recited in claim 12 , wherein each of the emitters are arranged along a ray extending from the detector.

14. The device as recited in claim 12 , wherein each of the emitters are located on a same side of the detector.

15. The device as recited in claim 11 , wherein each of the two emitters comprise a plurality of light sources.

16. The device as recited in claim 15 , wherein each of the two emitters comprise four light sources.

17. The device as recited in claim 15 , wherein each of the plurality of light sources within a given one of the at least two emitters has a different peak wavelength of emission.

18. A system including an electronic device and a hardware server, the system configured to generate at least one calibration factor for use in determining optical density and comprising:

a plurality of emitters, each having at least one light source, each of the emitters configured to emit light;

a detector configured to receive light and transmit data representative of the received light;

at least two of the plurality of emitters are spaced at different distances from the detector;

a processor coupled to the at least one emitter and the detector;

a non-transitory storage medium coupled to the processor and configured to store instructions to cause the device to repeat the following for each of the light sources:

emit light from one of the light sources of one of the emitters at a predetermined current towards an object that has a known optical density;

detect, at the detector, a portion of the emitted light corresponding to the predetermined current;

calculate, at the processor, a corresponding calibration factor based on the detected portion of emitted light through the object;

store the corresponding calibration factor in the non-transitory storage medium.

Assignments (6)
MERGER AND CHANGE OF NAME Recorded Jul 25, 2023
From: LVL TECHNOLOGIES, INC.; GIDEON MERGER SUB II, LLC
To: HAPPY HEALTH, INC.
Reel/Frame 064375/0243 →
MERGER Recorded Nov 20, 2019
From: PERFORMANCE ATHLYTICS, LLC
To: LVL TECHNOLOGIES, INC.
Reel/Frame 051063/0897 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2019
From: RAJAN, NITHIN O; FRECKLETON, DUSTIN M; XAVIER DA SILVEIRA, PAULO E; OLSON, BYRON
To: PERFORMANCE ATHLYTICS
Reel/Frame 050681/0139 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2019
From: RAJAN, NITHIN O.; FRECKLETON, DUSTIN M.; XAVIER DA SILVEIRA, PAULO E.; OLSON, BYRON
To: BSX ATHLETICS
Reel/Frame 050016/0660 →
CHANGE OF NAME Recorded Aug 9, 2019
From: PERFORMANCE ATHLYTICS, LLC.
To: LVL TECHNOLOGIES, INC.
Reel/Frame 050016/0720 →
CHANGE OF NAME Recorded Aug 9, 2019
From: BSX ATHLETICS
To: PERFORMANCE ATHLYTICS, LLC.
Reel/Frame 050018/0790 →
Continuity (2)
Provisional Application 62166571 · May 26, 2015
Related Publication 20180132767A1 · May 17, 2018
Cited By (1)
US 12,376,802