INFUSATE FRAME

1 . An infusate frame, comprising:

a rigid planar surface having at least a first lip disposed at a periphery of the planar surface and extending outwardly from the planar surface; the lip complementary to a ledge disposed on a dialysis machine; and

one or more openings cut-out on the planar surface; the one or more openings extending from a first side to a second side of the planar surface; the one or more openings having a size and/or shape complementary to one or more infusate container;

wherein a vertical axis of the one or more openings is aligned to a fluid connector disposed on the dialysis machine.

2 . The infusate frame of claim 1 , wherein the one or more openings are tapered inwardly.

3 . The infusate frame of claim 1 , wherein at least one opening is slotted to a periphery of the planar surface.

4 . The infusate frame of claim 3 , wherein the one or more openings are selected from a circular shape, a square shape, a triangular shape, or an oval shape.

5 . The infusate frame of claim 1 , further comprising one or more handles disposed on a periphery of the planar surface; the one or more handles extending upwardly from the planar surface.

6 . The infusate frame of claim 1 , wherein the one or more infusate container is selected from the group consisting of a sodium bicarbonate container, a sodium chloride container, and a cation infusate container.

7 . The infusate frame of claim 1 , further comprising at least one vertical support disposed on a periphery of the planar surface; the at least one vertical support extending upwardly from the periphery of the planar surface with a lip extending horizontally from the at least one vertical support.

8 . The infusate frame of claim 1 , comprising at least two openings cut-out on the planar surface, the at least two openings having different sizes or shapes.

9 . The infusate frame of claim 1 , further comprising a second lip opposedly positioned on the planar surface to the first lip.

10 . A dialysis system comprising:

the infusate frame of claim 1 , having one or more infusate containers containing one or more solute;

a dialysis machine, comprising:

(i) a dialysate flow path;

(ii) a receiving compartment for the infusate frame; and

(iii) one or more fluid connectors fluidly connectable to the one or more infusate containers and the dialysate flow path.

11 . The dialysis system of claim 10 , further comprising one or more pumps and one or more valves fluidly connectable to the one or more fluid connectors; the one or more pumps and one or more valves controlling fluid flow from the one or more infusate containers into the one or more fluid connectors.

12 . The dialysis system of claim 10 , further comprising a locking mechanism preventing the infusate frame from moving after insertion into the receiving compartment when the locking mechanism is in a locked state.

13 . The dialysis system of claim 10 , wherein the receiving compartment is sized or shaped complementary to a size or shape of the infusate frame.

14 . The dialysis system of claim 10 , wherein the infusate frame is formed integrally with the dialysis machine.

15 . The dialysis system of claim 10 , wherein the infusate frame is removable from the dialysis machine.

16 . The dialysis system of claim 11 , wherein at least one pump is a bidirectional pump.

17 . The dialysis system of claim 10 , wherein at least one fluid connector is disposed on a moveable paddle.

18 . The dialysis system of claim 10 , wherein the one or more infusate containers include a cation infusate container, a sodium chloride container, a sodium bicarbonate container, or combinations thereof.

19 . The dialysis system of claim 18 , wherein the sodium chloride container and sodium bicarbonate container are fluidly connectable to a valve; wherein the valve is fluidly connected to the dialysate flow path upstream of a sorbent cartridge and downstream of the sorbent cartridge.

20 . The dialysis system of claim 10 , wherein at least one fluid connector is a bi-directional connector.