IP Library Granted Patent US 11,324,753
Granted Patent B2
US 11,324,753 · App. 15/615,423 · Granted May 10, 2022

Method of treatment of attention deficit/hyperactivity disorder (ADHD)

Inventor: Christopher D. Breder (Bethesda, MD)
Assignee: Supernus Pharmaceuticals, Inc.
A61K31/5375A61K31/00
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Quick Facts
Patent No.
US 11,324,753
App. No.
15/615,423
Granted
May 10, 2022
Kind
B2
Abstract

The invention comprises a method for treatment of ADHD or ADHD-related disorders by a pharmaceutical agent exhibiting combined serotonergic or noradrenergic reuptake transporters and monoamine receptor activity.

Claims (9)

1. A method of antagonizing 5-HT7 and 5HT1B receptor activity in a patient suffering from ADHD, consisting of administering to the patient in need thereof a therapeutically effective amount of viloxazine, wherein the administration antagonizes both receptors.

2. The method of claim 1 , wherein the therapeutically effective amount is from about 20 to about 800 mg a day.

3. The method of claim 1 , wherein the therapeutically effective amount is from about 10 to about 600 mg a day.

4. The method of claim 3 , wherein the therapeutically effective amount is from about 150 to about 400 mg a day.

5. The method of claim 4 , wherein the therapeutically effective amount is from 150 to 300 mg a day.

6. The method of claim 1 , which provides an improved adverse effect profile.

7. The method of claim 1 , wherein the patient is a human child.

8. The method of claim 1 , wherein the patient further suffers from anxiety, depression, or bipolar disorder.

9. The method of claim 1 , wherein the patient further suffers from obsessive compulsive disorder, Tourette's Syndrome, or Post Traumatic Stress Disorder.

Assignments (1)
RELEASE OF SECURITY INTEREST Recorded Nov 30, 2017
From: U.S. BANK NATIONAL ASSOCIATION
To: SUPERNUS PHARMACEUTICALS, INC.
Reel/Frame 044552/0694 →