IP Library Granted Patent US 10,045,992
Granted Patent B2
US 10,045,992 · App. 15/626,518 · Granted Aug 14, 2018

7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5 (1h)-one, salts thereof and methods of using the same in combination therapy

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Quick Facts
Patent No.
US 10,045,992
App. No.
15/626,518
Granted
Aug 14, 2018
Kind
B2
Abstract

This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of such treatment a first therapeutic agent including compound (1): or a pharmaceutically acceptable salt thereof in combination with a second therapeutic agent, wherein the first therapeutic agent and the second therapeutic agent are administered either simultaneously or sequentially.

Claims (7)

1. A method of treatment comprising administering to a subject having genitourinary cancer in need of such treatment a pharmaceutically acceptable amount of compound (1):

or a pharmaceutically acceptable salt thereof, wherein the pharmaceutically acceptable amount of compound (1) is administered as a salvage therapy.

2. A method of treatment, comprising administering to a subject in need of such treatment a therapeutic agent comprising compound (1):

or a pharmaceutically acceptable salt thereof, wherein the treatment is for a genitourinary cancer.

3. The method of treatment according to claim 2 , wherein the genitourinary cancer is a gynecological malignancy.

4. The method of treatment according to claim 3 , wherein the gynecological malignancy is uterine cancer.

5. The method of treatment according to claim 4 , wherein the uterine cancer is endometrial cancer.

Assignments (2)
CONFIRMATORY PATENT ASSIGNMENT Recorded Oct 27, 2025
From: CHIMERIX, INC.; ONCOCEUTICS, INC.
To: JAZZ PHARMACEUTICALS IRELAND LIMITED
Reel/Frame 073333/0883 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 6, 2017
From: STOGNIEW, MARTIN; ALLEN, JOSHUA E.
To: ONCOCEUTICS, INC.
Reel/Frame 042912/0678 →
Cited By (1)
US 12,636,293