Methods for closing the left atrial appendage
Described here are devices, systems and methods for closing the left atrial appendage. Some of the methods described here utilize one or more guide members having alignment members to aid in positioning of a closure device. In general, these methods include advancing a first guide having a first alignment member into the left atrial appendage, advancing a second guide, having a second alignment member, into the pericardial space, aligning the first and second alignment members, advancing a left atrial appendage closure device into the pericardial space and adjacent to the left atrial appendage, and closing the left atrial appendage with the closure device. In these variations, the closure device typically has an elongate body having a proximal end and a distal end, and a closure element at least partially housed within the elongate body. The closure element comprises a loop defining a continuous aperture therethrough.
1. A method of closing a left atrial appendage comprising:
advancing an elongate body comprising a lumen therethrough to the left atrial appendage;
expanding a closure assembly beyond a distal end of the elongate body, the closure assembly comprising a support having a first end, a second end, and a loop with an aperture formed between the first end and the second end, wherein the support comprises a lumen extending between the first end and the second end and around the aperture, and a closure loop releasably housed in the lumen of the support;
advancing the closure assembly to encircle the left atrial appendage;
closing the closure assembly around the left atrial appendage;
retracting a proximal end of the closure loop to release the closure loop from the support; and
closing the left atrial appendage.
2. The method of claim 1 , further comprising confirming closure of the left atrial appendage.
3. The method of claim 1 , wherein the elongate body is advanced under visualization.
4. The method of claim 1 , wherein the elongate body is advanced from a sub-xiphoid approach.
5. The method of claim 1 , wherein the closure assembly is at least partially disposed within the lumen of the elongate body during advancement.
6. The method of claim 5 , wherein expanding the closure assembly comprises advancing the closure assembly distally through the lumen of the elongate body.
7. The method of claim 1 , wherein advancing the elongate body to the left atrial appendage comprises advancing the elongate body through a lumen of a guide sheath.
8. The method of claim 1 , wherein the support further comprises a second lumen.
9. The method of claim 1 , wherein the closure loop comprises a suture loop.
10. The method of claim 1 , wherein expanding the closure assembly comprises increasing a size of the aperture of the loop.
11. The method of claim 1 , the closure assembly further comprising a closure element.
12. The method of claim 11 , wherein a portion of the closure element is housed within the support.
13. The method of claim 1 , wherein the elongate body houses a suture hook coupled to the closure loop.
14. The method of claim 1 , wherein a proximal end of the elongate body is coupled to a handle.