IP Library Granted Patent US 10,315,911
Granted Patent B2
US 10,315,911 · App. 15/647,547 · Granted Jun 11, 2019

Spacer for side loaded EWOD device

Inventors: Lesley Anne Parry-Jones (Oxford, GB); Emma Jayne Walton (Oxford, GB)
Assignee: Sharp Life Science (EU) Limited
B81B1/00B01L3/50273B01L2200/025B01L2200/10B01L2300/0809B01L2300/0887B01L2300/161B01L2400/0427B81B7/0061B81B2201/058B81B2203/04B81B2207/056
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Quick Facts
Patent No.
US 10,315,911
App. No.
15/647,547
Granted
Jun 11, 2019
Kind
B2
Abstract

An EWOD device includes a first and second substrate assemblies, and a spacer that spaces apart the first substrate assembly from the second substrate assembly to define a channel between them. The spacer defines fluid input ports that are in fluid communication with the channel, and the spacer is configured for directing fluid from the fluid input ports into the channel. The spacer has a combed spacer configuration to define the fluid input ports, including alternating teeth that extend into the channel from a base region, and the teeth isolate adjacent fluid input ports from each other. The spacer may contact only a portion of the first and second substrate assemblies to form a spacerless region within the EWOD device, and the spacer includes regions that are in contact with both the first and second substrate assemblies and extend into the channel to define a cell-gap of the channel.

Claims (24)

1. An electrowetting on dielectric (EWOD) device comprising:

a first substrate assembly and a second substrate assembly; and

a spacer that spaces apart the first substrate assembly from the second substrate assembly to define a channel between the first and second substrate assemblies;

wherein the spacer defines a plurality of fluid input ports that are in fluid communication with the channel, and the spacer is configured for directing fluid from the fluid input ports into the channel; and

wherein the spacer has a combed spacer configuration to define the plurality of fluid input ports, the combed spacer configuration including alternating teeth that extend into the channel from a base region.

2. The EWOD device of claim 1 , wherein externally from the channel the teeth separate adjacent fluid input ports from each other such that adjacent fluid input ports are not in fluid communication with each other except through the channel.

3. The EWOD device of claim 1 , wherein the spacer contacts only a portion of a perimeter of the first and second substrate assemblies to form a spacerless region in which there is no spacer at the perimeter of the first and second substrate assemblies.

4. The EWOD device of claim 3 , wherein the spacer includes regions that are in contact with both the first and second substrate assemblies and extend into the channel so as to define a uniform cell-gap of the channel.

5. The EWOD device of claim 1 , further comprising an exit port configured as an extension of the spacer that forms a fluid passage into the channel.

6. The EWOD device of claim 1 , wherein a portion of the spacer opposite of the channel that defines the fluid input ports is rounded in shape.

7. The EWOD device of claim 1 , wherein:

one of the first substrate assembly or the second substrate assembly includes thin film electronics for applying an electrowetting voltage into the channel, the thin film electronics defining an active area within the channel; and

the substrate assembly including the thin film electronics defines an inactive border region adjacent to the active area in which the electrowetting voltage is not applicable.

8. The EWOD device of claim 7 , wherein the alternating teeth extend into the channel from the base region beyond the inactive border region and into the active area.

9. The EWOD device of claim 7 , wherein the inactive border region is symmetric on at least some opposing edges of the substrate assembly including the thin film electronics.

10. The EWOD device of claim 7 , wherein the inactive border region is asymmetric to have different sizes on differing edges of the substrate assembly including the thin film electronics.

11. The EWOD device of claim 7 , wherein the substrate assembly including the thin film electronics has a ridge adjacent to the inactive border region.

12. The EWOD device of claim 7 , wherein the first substrate assembly is an upper substrate assembly and includes the thin film electronics.

13. The EWOD device of claim 7 , wherein the second substrate assembly is a lower substrate assembly and includes the thin film electronics.

14. The EWOD device of claim 7 , wherein at least one edge the substrate assembly incorporating the thin film electronics is co-incident with the active area.

15. The EWOD device of claim 1 , wherein:

one of the first substrate assembly or the second substrate assembly includes thin film electronics for applying an electrowetting voltage into the channel, the thin film electronics defining an active area within the channel; and

a portion of the active area extends beyond the substrate assembly that does not include the thin film electronics.

16. The EWOD device of claim 15 , wherein the second substrate assembly is a lower substrate assembly and includes the thin film electronics.

Assignments (4)
CHANGE OF APPLICANT'S ADDRESS Recorded Feb 3, 2022
From: SHARP LIFE SCIENCE (EU) LIMITED
To: SHARP LIFE SCIENCE (EU) LIMITED
Reel/Frame 058948/0187 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER 14647547 PREVIOUSLY RECORDED AT REEL: 043167 FRAME: 0689. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT . Recorded Jul 13, 2021
From: PARRY-JONES, LESLEY ANNE; WALTON, EMMA JAYNE
To: SHARP LIFE SCIENCE (EU) LIMITED
Reel/Frame 057848/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2019
From: PARRY-JONES, LESLEY ANNE; WALTON, EMMA JAYNE
To: SHARP LIFE SCIENCE (EU) LIMITED
Reel/Frame 049606/0313 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 2, 2017
From: PARRY-JONES, LESLEY ANNE; WALTON, EMMA JAYNE
To: SHARP LIFE SCIENCE (EU) LIMITED
Reel/Frame 043167/0689 →
Continuity (1)
Related Publication 20190016587A1 · Jan 17, 2019