IP Library Granted Patent US 10,093,627
Granted Patent B2
US 10,093,627 · App. 15/661,143 · Granted Oct 9, 2018

Tetrahydroquinoline derivatives and their use as Epac inhibitors

Inventors: Frank Lezoualc'h (Toulouse, FR); Rodolphe Fischmeister (Chatenay-Malabry, FR); Malik Bisserier (Toulouse, FR); Pascal Bouyssou (Orleans, FR); Jean-Paul Blondeau (Chatenay-Malabry, FR); Delphine Courilleau (Chatenay-Malabry, FR)
Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE PAUL SABATIER TOULOUSE III; UNIVERSITE PARIS-SUD; UNIVERSITE D'ORLEANS
C07D215/14A61K31/47C07D215/08C07D215/18
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Quick Facts
Patent No.
US 10,093,627
App. No.
15/661,143
Granted
Oct 9, 2018
Kind
B2
Abstract

The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.

Claims (1)

1. A composition, comprising a pharmaceutically acceptable carrier, and compound having the following formula:

Assignments (2)
MERGER Recorded Aug 22, 2022
From: UNIVERSITE DE PARIS 11 - PARIS SUD (ALSO NAMED UNIVERSITÉ PARIS-SUD)
To: UNIVERSITE PARIS-SACLAY
Reel/Frame 060856/0245 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2017
From: LEZOUALC'H, FRANK; FISCHMEISTER, RODOLPHE; BISSERIER, MALIK; BOUYSSOU, PASCAL; BLONDEAU, JEAN-PAUL; COURILLEAU, DELPHINE
To: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE PAUL SABATIER TOULOUSE III; UNIVERSITE PARIS-SUD; UNIVERSITE D'ORLEANS
Reel/Frame 043115/0713 →
Priority Claims (1)
EP 12306201 · Oct 2, 2012 · regional
Continuity (2)
Continuation 14432768
Related Publication 20180009757A1 · Jan 11, 2018