IP Library Granted Patent US 10,537,426
Granted Patent B2
US 10,537,426 · App. 15/668,559 · Granted Jan 21, 2020

Prosthetic heart valve

Inventors: Meni Iamberger (Kfar Saba, IL); Aviram Baum (Tel Aviv, IL); Boaz Harari (Ganey Tikva, IL); Ilia Hariton (Zichron Yaackov, IL)
Assignee: CARDIOVALVE LTD.
A61F2/2418A61F2/24A61F2/2412A61F2/2436A61F2/86A61F2/01A61F2230/0063A61F2240/001A61F2240/004
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Quick Facts
Patent No.
US 10,537,426
App. No.
15/668,559
Granted
Jan 21, 2020
Kind
B2
Abstract

A tubular valve body has an upstream end and a downstream end, and has a central longitudinal axis, and defines a lumen along the axis. Prosthetic leaflets are disposed within the lumen, and are configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction. The valve body has a cellular structure defined by a plurality of joists connected at nodes, the joists and nodes delimiting cells of the cellular structure. The nodes include minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected. The cells of the cellular structure comprise a first circumferential row of first-row cells. Each of the first-row cells is connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and is longitudinally delimited by two of the minor nodes. Other embodiments are described.

Claims (41)

1. Apparatus, comprising:

a valve body that:

is tubular,

has an upstream end, a downstream end, and a central longitudinal axis, and

defines a lumen along the central longitudinal axis; and

a plurality of prosthetic leaflets, disposed within the lumen, and configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction, wherein:

the valve body has a cellular structure defined by a plurality of joists connected at a plurality of nodes, the joists and nodes delimiting cells of the cellular structure, the plurality of nodes including minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected,

the cells of the cellular structure comprise a first circumferential row of first-row cells, each of the first-row cells (i) being connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and (ii) being longitudinally delimited by two of the minor nodes,

the cellular structure further comprises a second circumferential row of second-row cells, each of the second-row cells (i) being connected to each of its circumferentially-adjacent second-row cells at a respective one of the major nodes, and (ii) being longitudinally delimited by at least one of the major nodes, and

each of the first-row cells and each of the second-row cells is delimited by exactly four nodes.

2. The apparatus according to claim 1 , wherein at the minor nodes exactly two joists are connected.

3. The apparatus according to claim 1 , wherein at the major nodes exactly six joists are connected.

4. The apparatus according to claim 1 , wherein, for each of the first-row cells, the first-row cell is not connected to another cell at the two minor nodes that longitudinally delimit the first-row cell.

5. The apparatus according to claim 1 , wherein the apparatus comprises a frame assembly that comprises (i) an inner frame that defines the valve body, and (ii) an outer frame that circumscribes the valve body, and is coupled to the inner frame by being fixed to a plurality of the major nodes of the valve body.

6. The apparatus according to claim 1 , wherein each of the second-row cells is also longitudinally delimited by one of the minor nodes.

7. The apparatus according to claim 1 , wherein each of the respective major nodes at which the circumferentially-adjacent first-row cells are connected is also a major node that longitudinally-delimits a second-row cell.

8. The apparatus according to claim 1 , wherein all the cells of the cellular structure of the valve body are either first-row cells or second-row cells.

9. The apparatus according to claim 1 , wherein the apparatus comprises a frame assembly that comprises (i) an inner frame that defines the valve body, and (ii) an outer frame that circumscribes the valve body, and is coupled to the inner frame by being fixed to the major nodes at which the circumferentially-adjacent second-row cells are connected.

10. The apparatus according to claim 1 , wherein the first and second circumferential rows are disposed at opposing ends of the valve body.

11. The apparatus according to claim 10 , wherein the first circumferential row is disposed at the upstream end of the valve body, and the second circumferential row is disposed at the downstream end of the valve body.

12. Apparatus, comprising:

a valve body that:

is tubular,

has an upstream end, a downstream end, and a central longitudinal axis, and

defines a lumen along the central longitudinal axis; and

a plurality of prosthetic leaflets, disposed within the lumen, and configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction, wherein:

the tubular valve body has a cellular structure defined by a plurality of joists connected at a plurality of nodes, the joists and nodes delimiting cells of the cellular structure, the plurality of nodes including minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected,

the cells of the cellular structure comprise a first circumferential row of first-row cells, each of the first-row cells (i) being connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and (ii) being longitudinally delimited by two of the minor nodes,

the cellular structure further comprises a second circumferential row of second-row cells, each of the second-row cells (i) being connected to each of its circumferentially-adjacent second-row cells at a respective one of the major nodes, and (ii) being longitudinally delimited by at least one of the major nodes, and

the second circumferential row is rotationally offset with respect to the first circumferential row, such that the second-row cells are rotationally staggered with respect to the first-row cells.

13. The apparatus according to claim 12 , wherein at the minor nodes exactly two joists are connected.

14. The apparatus according to claim 12 , wherein at the major nodes exactly six joists are connected.

15. The apparatus according to claim 12 , wherein, for each of the first-row cells, the first-row cell is not connected to another cell at the two minor nodes that longitudinally delimit the first-row cell.

16. The apparatus according to claim 12 , wherein the apparatus comprises a frame assembly that comprises (i) an inner frame that defines the valve body, and (ii) an outer frame that circumscribes the valve body, and is coupled to the inner frame by being fixed to a plurality of the major nodes of the valve body.

17. The apparatus according to claim 12 , wherein each of the second-row cells is also longitudinally delimited by one of the minor nodes.

18. The apparatus according to claim 12 , wherein each of the respective major nodes at which the circumferentially-adjacent first-row cells are connected is also a major node that longitudinally-delimits a second-row cell.

19. The apparatus according to claim 12 , wherein all the cells of the cellular structure of the valve body are either first-row cells or second-row cells.

20. The apparatus according to claim 12 , wherein the apparatus comprises a frame assembly that comprises (i) an inner frame that defines the valve body, and (ii) an outer frame that circumscribes the valve body, and is coupled to the inner frame by being fixed to the major nodes at which the circumferentially-adjacent second-row cells are connected.

21. The apparatus according to claim 12 , wherein each of the first-row cells and each of the second-row cells is delimited by exactly four nodes.

22. The apparatus according to claim 12 , wherein the first and second circumferential rows are disposed at opposing ends of the valve body.

23. The apparatus according to claim 22 , wherein the first circumferential row is disposed at the upstream end of the valve body, and the second circumferential row is disposed at the downstream end of the valve body.

Assignments (4)
SECURITY INTEREST Recorded Jun 10, 2021
From: CARDIOVALVE LTD.
To: BEST, LAWRENCE C.; OXO CAPITAL VALVE VENTURES LLC; PEREGRINE VC INVESTMENTS IV (IL) L.P.; PEREGRINE VC INVESTMENTS IV (US INVESTORS) L.P; PEREGRINE VC INVESTMENTS IV (OTHER INVESTORS) L.P.; NGN BIOMED OPPORTUNITY II, L.P.; IF A PE FUND II, LP; IF A PE FUND II US, LP
Reel/Frame 056539/0833 →
CHANGE OF NAME Recorded Sep 10, 2018
From: MITRALTECH LTD.
To: CARDIOVALVE LTD.
Reel/Frame 046826/0175 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2017
From: IAMBERGER, MENI; BAUM, AVIRAM; HARARI, BOAZ; AYVAZIAN, ARAM; HARITON, ILIA
To: MITRALTECH LTD.
Reel/Frame 044239/0763 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2017
From: IAMBERGER, MENI; BAUM, AVIRAM; HARARI, BOAZ; AYVAZIAN, ARAM; HARITON, ILIA
To: MITRALTECH LTD.
Reel/Frame 043191/0793 →
Continuity (1)
Related Publication 20190038404A1 · Feb 7, 2019
Cited By (8)
US 12,232,958 US 12,310,575 US 12,350,406 US 12,357,459 US 12,396,851 US 12,458,493 US 12,569,335 US 12,611,305