Drug compositions comprising an anti-parasitic and proton pump inhibitor
Described herein are pharmaceutical compositions including a proton pump inhibitor and an antiparasitic drug. In some embodiments, the compositions can be formulated as a non-solid for oral administration. The compositions can be used to treat gastrointestinal conditions. Methods of treatment using the compositions are also described.
1. A composition including:
a paste including about 22% w/v omeprazole, about 30% w/v fenbendazole, and a wetting agent formulated in a melted polyethylene glycol base agent for oral administration to a mammal.
2. The composition of claim 1 , wherein the wetting agent is a polyethylene glycol.
3. The composition of claim 1 , further including sodium sulfite.
4. The composition of claim 1 , further including carboxymethyl cellulose.
5. The composition of claim 1 , further including sodium bicarbonate.
6. The composition of claim 1 , further including a flavoring agent.
7. The composition of claim 1 , wherein the mammal is a horse.
8. The composition of claim 1 , wherein the mammal is a camel.
9. An equine composition including a paste including a melted polyethylene glycol base agent including 22% omeprazole, 30% fenbendazole, a wetting agent, and carboxymethyl cellulose formulated for administration from an oral syringe.
10. A composition including:
a paste including about 22% w/v omeprazole, about 30% w/v fenbendazole, carboxymethylcellulose, a preservative, and a wetting agent formulated in a melted polyethyleneglycol base agent for oral administration to a mammal.