Aseptic coupling devices

1. A method of using an aseptic coupling device, the method comprising:

removing, from a front face of the aseptic coupling device, a membrane,

wherein prior to the removing: (i) a first portion of the membrane was attached directly to the front face completely around an opening defined by the front face to thereby cover the opening, (ii) a fold in the membrane separated the first portion of the membrane from a second portion of the membrane, and (iii) a low friction member defining an aperture was positioned between the first and second portions of the membrane, and wherein the second portion of the membrane covered the aperture.

2. The method of claim 1 , wherein the low friction member reduces friction between the first and second portions of the membrane during the removing.

3. The method of claim 1 , wherein the low friction member does not fold during the removing.

4. The method of claim 1 , wherein an entirety of the membrane is separated from the aseptic coupling device after the removing.

5. The method of claim 1 , further comprising:

prior to the removing, decoupling a cover releasably coupled with the aseptic coupling device,

wherein, prior to the decoupling, the cover is coupled with the main coupling body and holding the membrane against the front face.

6. The method of claim 1 , wherein the aseptic coupling device is a first aseptic coupling device, and wherein the method further comprises:

prior to the removing, coupling the first aseptic coupling device to a second aseptic coupling device,

wherein, after the removing, the first and second aseptic coupling devices are coupled together to define a fluid pathway through the first and second aseptic coupling devices.

7. The method of claim 1 , wherein the low friction member is made of polytetrafluoroethylene.

8. The method of claim 1 , wherein the membrane includes a single fold.

9. The method of claim 1 , wherein the low friction member is attached to the second portion of the membrane.