Picolinamide N-oxide compounds with fungicidal activity
View Patent ↗This disclosure relates to picolinamide N-oxides of Formula I and their use as fungicides.
1. A compound of Formula I,
wherein:
R 1 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1 or multiple R 6 ;
R 2 is hydrogen, C 1 -C 5 alkyl or cycloalkyl, each optionally substituted with 0, 1 or multiple R 6 ;
R 3 is alkyl, cycloalkyl, aryl or heteroaryl, each optionally substituted with 0, 1 or multiple R 6 ;
R 4 is hydrogen, halo, hydroxyl, alkyl, or alkoxy;
R 5 is alkyl, cycloalkyl, aryl, heteroaryl, alkoxy, aryloxy, heteroaryloxy, each optionally substituted with 0, 1 or multiple R 6 ;
R 6 is hydrogen, alkyl, aryl, acyl, halo, alkoxy, or heterocyclyl, each optionally substituted with 0, 1 or multiple R 7 ;
R 7 is hydrogen, alkyl, aryl, acyl, halo, alkoxy, or heterocyclyl; and
R 8 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1 or multiple R 6 .
2. A compound according to claim 1 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl.
3. A compound according to claim 2 , wherein R 2 is C 1 -C 5 alkyl.
4. A compound according to claim 2 , wherein R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 .
5. A compound according to claim 2 , wherein R 4 is hydrogen.
6. A compound according to claim 2 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl, R 2 is C 1 -C 5 alkyl, R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 , and R 4 is hydrogen.
7. A composition for the control of a fungal pathogen including mixtures of at least one of the compounds of claim 1 and another pesticide including fungicides, insecticides, nematocides, miticides, arthropodicides, bactericides, and combinations thereof.
8. A composition for the control of a fungal pathogen including mixtures of at least one of the compounds of claim 6 and another pesticide including fungicides, insecticides, nematocides, miticides, arthropodicides, bactericides, and combinations thereof.