Implant delivery system and method of use

1. An implant delivery system, comprising:

a catheter having a delivery lumen;

a pusher member slidably disposed in the catheter delivery lumen;

a retaining member coupled to a distal end portion of the pusher member, the retaining member configured to retain an expandable implant in a collapsed configuration on the pusher member for delivery of the implant through the catheter delivery lumen; and

an expandable actuator coupled to the distal end portion of the pusher member and operatively associated with the retaining member, wherein expansion of the actuator causes the retaining member to disengage from the implant carried on the pusher member, to thereby allow the implant to expand from the collapsed configuration,

wherein the actuator comprises an inflatable membrane, and the pusher member comprises an inflation lumen in communication with an interior region defined by the membrane, and wherein the retaining member is affixed to the membrane.

2. The system of claim 1 , further comprising the expandable implant carried on the pusher member, the retaining member comprising a first end attached to the pusher member at a location distal to the implant, and a second end releasably engaging the implant to thereby retain the implant in the collapsed configuration on the pusher member, wherein the retaining member is biased to retain the implant in the collapsed configuration on the pusher member.

3. The system of claim 2 , wherein the expandable implant comprises a tubular body.

4. An implant delivery system, comprising:

a catheter having a delivery lumen;

a pusher member slidably disposed in the catheter delivery lumen;

an expandable implant carried on a distal end portion of the pusher member;

a plurality of retention members, each having a first end attached to the pusher member at a location distal to the implant, and a second end releasably engaging the implant to thereby retain the implant in a collapsed configuration on the pusher member for delivery of the implant through the catheter delivery lumen; and

an inflatable membrane attached to the pusher member and having an exterior surface affixed to the respective retention members, the pusher member comprising an inflation lumen in communication with an interior region defined by the membrane, wherein inflation of the membrane causes the retaining members to disengage the implant and thereby allow the implant to expand from the collapsed configuration.

5. The system of claim 4 , wherein the respective first ends of the retention members are pivotally attached to the pusher member.

6. The system of claim 4 , wherein the retention members are biased to retain the implant in the collapsed configuration on the pusher member.

7. The system of claim 4 , wherein the pusher member comprises a stop member proximally disposed to the expandable implant carried on the pusher member, wherein the stop member limits translation movement of the implant in its collapsed configuration.

8. The system of claim 7 , wherein the stop member comprises an annular ring or a plurality of protrusions disposed on the pusher member.

9. The system of claim 4 , further comprising a guidewire disposed within the inflation lumen of the pusher member, and a seal member disposed distally to the expandable actuator of the pusher member, wherein the seal member has an opening therethrough to allow passage of the guidewire.