IP Library Granted Patent US 10,889,830
Granted Patent B2
US 10,889,830 · App. 15/709,691 · Granted Jan 12, 2021

Binary insecticidal Cry toxins

Inventors: Kenneth E. Narva (Zionsville, IN); Huarong Li (Zionsville, IN); Sek Yee Tan (Carmel, IN); Tao Xu (Indianapolis, IN); Timothy D. Hey (Zionsville, IN); Vimbai Chikwana (Indianapolis, IN); Sarah E. Worden (Indianapolis, IN)
Assignee: DOW AGROSCIENCES LLC
C12N15/8286A01N25/006A01N63/10C07K14/325C12N9/93C12N15/8213G01N2430/12Y02A40/162
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Quick Facts
Patent No.
US 10,889,830
App. No.
15/709,691
Granted
Jan 12, 2021
Kind
B2
Abstract

The subject invention concerns new classes of insecticidally-active proteins and the polynucleotide sequences which encode these proteins. More specifically, insecticidal proteins of approximately 12-24 kDa and of approximately 12-14 kDa are used for controlling corn rootworms. The subject invention includes methods and transgenic plants for controlling Western Corn Rootworm and other coleopteran insects.

Claims (6)

1. A method for controlling a coleopteran pest which comprises exposing the gut of said coleopteran pest to an effective combination of a potentiator protein and a toxin protein, wherein the potentiator protein comprises a functional amino acid sequence comprising a polypeptide having at least 95% sequence identity to SEQ ID NO:2.

2. The method of claim 1 wherein the toxin protein comprises any one of the toxin proteins selected from the group consisting of SEQ ID NOs: 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 71, 74, 76, 82, 86, 88, 91, 93, 95, 97, 99, 101, 103, and 105.

3. The method of claim 1 wherein the toxin protein is selected from the group consisting of SEQ ID NOs: 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 71, 74, 76, 82, 86, 88, 91, 93, 95, 97, 99, 101, 103, and 105.

4. The method of claim 1 wherein the coleopteran pest is western com rootworm (WCR, Diabrotica virgifera virgifera LeConte).

5. The method of claim 2 wherein the coleopteran pest is western com rootworm (WCR, Diabrotica virgifera virgifera LeConte).

6. The method of claim 3 wherein the coleopteran pest is western com rootworm (WCR, Diabrotica virgifera virgifera LeConte).

Assignments (2)
CHANGE OF NAME Recorded Nov 8, 2021
From: DOW AGROSCIENCES LLC
To: CORTEVA AGRISCIENCE LLC
Reel/Frame 058044/0184 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2017
From: NARVA, KENNETH; LI, HUARONG; TAN, SEK YEE; XU, TAO; HEY, TIMOTHY D.; CHIKWANA, VIMBAI; WORDEN, SARAH E.
To: DOW AGROSCIENCES LLC
Reel/Frame 044027/0504 →
Continuity (2)
Provisional Application 62402316 · Sep 30, 2016
Related Publication 20180094277A1 · Apr 5, 2018