Injector manifold
A device and method for purification of information or particles from a sample and provides a device for performing washing steps in automated analyzer systems, the device comprising a multilayer unit with liquid channel and valves. The multilayer unit may comprise three layer.
1. A device for performing washing steps in automated analyzer systems, the device comprising:
a multilayer unit with at least one layer, wherein the at least one layer of the multilayer unit comprises:
at least one valve mounted to a first channel of the at least one layer, wherein the first channel is connected to at least one injector for injecting a washing buffer into a cuvette or vessel, and
a second channel providing a rinsing buffer, wherein the second channel is separated from the first channel and encloses an aspiration probe which is movably arranged along its longitudinal axis within an aspiration probe guiding which is a bore in the at least one layer for cleaning the aspiration probe that was in contact with liquids from the cuvette or vessel.
2. The device of claim 1 , wherein the multilayer unit comprises three layers, an upper layer, a middle layer and a lower layer.
3. The device of claim 1 , wherein the at least one layer of the multilayer unit comprises tubing sockets and at least one inlet and outlet for the at least one valve.
4. The device of claim 1 , wherein the at least one layer of the multilayer unit comprises an inlet and outlet connected to the second channel providing the rinsing buffer.
5. The device of claim 1 , wherein the at least one layer of the multilayer unit comprises at least one injector connected to the at least one valve.
6. The device of claim 1 , wherein the at least one layer comprises at least one acceptance for sensors adjacent to the bore.
7. The device of claim 1 , wherein the at least one valve is fixed to the at least one layer of the multilayer unit.
8. The device of claim 4 , wherein the at least one layer comprises openings for a tubing of washing buffer and the inlet and outlet of rinsing buffer.
9. The device of claim 1 , comprising at least one sensor for measuring liquid amounts, flow rates, pressure, conductivity or temperature.
10. The device of claim 9 , wherein the at least one sensor is integrated directly in the first channel between the at least one valve and the at least one injector.
11. A method for performing washing steps in an automated analyzer system, comprising the steps of
a) providing a rinsing buffer for cleaning through a multilayer unit with at least one layer, wherein the at least one layer of the multilayer unit comprises:
at least one valve mounted to a first channel of the at least one layer, wherein the first channel is connected to at least one injector for injecting a washing buffer into a cuvette or vessel; and
a second channel for providing a rinsing buffer, wherein the second channel is separated from the first channel and encloses an aspiration probe which is movably arranged along its longitudinal axis within an aspiration probe guiding which is a bore in the at least one layer for cleaning the aspiration probe that was in contact with liquids from the cuvette or vessel;
b) aspiration of the washing buffer from the cuvette or vessel by at least one aspiration probe that is arranged movable across the multilayer unit;
c) moving the aspiration probe along their longitudinal axis through an aspiration probe guiding; and
d) cleaning the aspiration probe in the aspiration probe guiding by flushing the aspiration probe with the rinsing buffer.
12. The method of claim 11 , additionally comprising the step of detecting liquid amounts, flow rates, pressure, conductivity or temperature with at least one sensor.