IP Library Granted Patent US 10,772,490
Granted Patent B2
US 10,772,490 · App. 15/714,048 · Granted Sep 15, 2020

Monitoring device and method of operating the same

Inventors: Daisuke Yamashita (Hamamatsu, JP); Yutaka Yamashita (Hamamatsu, JP); Yukio Ueda (Hamamatsu, JP); Yoshinori Tamaoki (Hamamatsu, JP)
Assignee: HAMAMATSU PHOTONICS K.K.
A61B1/07A61B5/0084A61B5/0261A61B18/245A61M25/0043G02B6/0001G02B6/10G02B6/241A61B18/26A61B2018/00785A61N2005/0602
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Quick Facts
Patent No.
US 10,772,490
App. No.
15/714,048
Granted
Sep 15, 2020
Kind
B2
Abstract

A device for radiating pulsed light toward a thrombus in a blood vessel includes a light source configured to output monitoring light to be radiated into the blood vessel, a light detector configured to detect returned light of the monitoring light and output a detection signal, and a computer configured to acquire a time waveform, which is a change in an intensity of the returned light over time, based on the detection signal, wherein the computer is configured to obtain a parameter on the basis of the time waveform and evaluates a reaction in the blood vessel according to the radiation of the pulsed light on the basis of the parameter.

Claims (29)

1. A device for radiating pulsed light toward a thrombus in a blood vessel, the device comprising:

a first light source configured to output the pulsed light to be radiated toward the thrombus in the blood vessel;

a second light source configured to output monitoring light to be radiated into the blood vessel;

a light detector configured to detect returned light of the monitoring light and output a detection signal, the returned light of the monitoring light being reflected and/or scattered by a bubble generated in the blood vessel by the pulsed light radiated toward the thrombus; and

a computer configured to acquire a time waveform, which is a change in an intensity of the returned light over time, based on the detection signal,

wherein the computer is configured to obtain a parameter on the basis of the time waveform and evaluates a reaction in the blood vessel according to the radiation of the pulsed light on the basis of the parameter, and

wherein the parameter is a waveform area of the time waveform.

2. The device according to claim 1 , wherein the parameter further includes at least one of a convergence Lime in the time waveform, a peak time in the time waveform, a peak intensity in the time waveform, a waveform pattern in the time waveform, and presence or absence of a peak in the time waveform.

3. The device according to claim 1 , wherein the monitoring light is continuous wave light.

4. The device according to claim 2 , wherein the monitoring light is continuous wave light.

5. The device according to claim 1 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

6. The device according to claim 2 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

7. The device according to claim 3 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

8. The device according to claim 4 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

9. A method for radiating pulsed light toward a thrombus in a blood vessel, the method comprising:

radiating the pulsed light toward the thrombus in the blood vessel;

radiating monitoring light into the blood vessel;

detecting returned light of the monitoring light by a light detector and outputting a detection signal, the returned light of the monitoring light being reflected and/or scattered by a bubble generated in the blood vessel by radiating the pulsed light toward the thrombus;

acquiring a time waveform, which is a change in an intensity of the returned light over time, based on the detection signal;

obtaining a parameter based on the time waveform; and

evaluating a reaction in the blood vessel according to the radiation of the pulsed light based on the parameter,

wherein the parameter is a waveform area of the time waveform.

10. The method according to claim 9 , wherein the parameter further includes at least one of a convergence time in the time waveform, a peak time in the time waveform, a peak intensity in the time waveform, a waveform pattern in the time waveform, and presence or absence of a peak in the time waveform.

11. The method according to claim 9 , wherein the monitoring light is continuous wave light.

12. The method according to claim 10 , wherein the monitoring light is continuous wave light.

13. The method according to claim 9 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

14. The method according to claim 10 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

15. The method according to claim 11 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

16. The method according to claim 12 , wherein the monitoring light has a wavelength in a range of 600 nm to 1300 nm.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2017
From: YAMASHITA, DAISUKE; YAMASHITA, YUTAKA; UEDA, YUKIO; TAMAOKI, YOSHINORI
To: HAMAMATSU PHOTONICS K.K.
Reel/Frame 043681/0203 →
Priority Claims (1)
JP 2016-188257 · Sep 27, 2016 · national
Continuity (1)
Related Publication 20180084982A1 · Mar 29, 2018