IP Library Granted Patent US 9,927,346
Granted Patent B2
US 9,927,346 · App. 15/715,464 · Granted Mar 27, 2018

Flow cytometer system including flow cytometer, autosampler and system integration structure

Inventors: Garrett S. Wilson (Erie, CO); Braden L. Smith (Lafayette, CO); Michael A. Artinger (Boulder, CO); Francis Kevin Kohlmeier (Tigard, OR); Christopher H. Converse (Boulder, CO)
Assignee: IntelliCyt Corporation
G01N15/1404B01L3/502G01N15/1459G01N35/1095B01L2200/026B01L2300/0609B01L2300/0858B01L2300/0867B01L2300/123G01N2015/1409
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,927,346
App. No.
15/715,464
Granted
Mar 27, 2018
Kind
B2
Abstract

A flow cytometer system includes a flow cytometer, an autosampler and a system integration structure to accommodate interconnection and interface of the flow cytometer and autosampler for operation together and providing for convenient interface with equipment for handling process liquids.

Claims (16)

1. A flow cytometer system, comprising:

a flow cytometer with a sample inlet for receiving a sample fluid for flow cytometry analysis of the sample fluid for particles within the sample fluid;

an autosampler in fluid communication with the sample inlet of the flow cytometer and operative to automatically provide a series of batches of sample fluid to the flow cytometer for flow cytometry analysis;

a system integration structure, comprising:

an upper shelf disposed above the autosampler and on which the flow cytometer is supported above the autosampler;

a container rack comprising a plurality of container receptacles to receive a corresponding plurality of process liquid containers to provide a source of process liquid to and receive used process liquid from operations of the flow cytometer and autosampler; and

a routing channel to route fluid conduits from process liquid containers toward the flow cytometer and the autosampler when the liquid containers are received in the container rack;

at least one access opening into the routing channel to provide access for routing the fluid conduits from outside of the routing channel to inside the routing channel, wherein:

the routing channel extends from the at least one access opening in a upward direction for routing of one or more of the fluid conduits to the flow cytometer located at a higher elevation than the at least one opening;

the routing channel extends from the at least one access opening in a downward direction for routing one or more of the fluid conduits to the autosampler; and

the at least one access opening is located at a vertically elevated position relative to the receptacles of the container rack; and

a plurality of the process liquid containers received within the receptacles of the container rack and the fluid conduits in fluid communication with the process liquid containers;

and wherein:

each said process fluid container is in fluid communication with the flow cytometer or the autosampler through a said fluid conduit routed through the routing channel; and

at least two of the received process liquid containers are each in fluid communication with at least two said fluid conduits, wherein one of said fluid conduits to a said process liquid container provides liquid from the said process liquid container to the flow cytometer or the autosampler and another of said fluid conduits is in fluid communication through the flow cytometer with a source of compressed gas to provide compressed gas to the said process liquid container from the flow cytometer to pressurize the said process liquid container.

2. The flow cytometer system according to claim 1 , comprising a support member supporting the upper shelf, wherein the routing channel passes through the support member, wherein the at least one access opening is through a side wall of the support member to provide access for routing the fluid conduits from outside of the support member to the routing channel in the support member.

Assignments (7)
MERGER AND CHANGE OF NAME Recorded Feb 20, 2019
From: INTELLICYT CORPORATION; ESSEN INSTRUMENTS, INC. D/B/A ESSEN BIOSCIENCE, INC.
To: ESSEN INSTRUMENTS, INC. D/B/A ESSEN BIOSCIENCE, INC.
Reel/Frame 048387/0239 →
MERGER AND CHANGE OF NAME Recorded Feb 20, 2019
From: INTELLICYT CORPORATION; ESSEN INSTRUMENTS, INC. D/B/A ESSEN BIOSCIENCE, INC.
To: ESSEN INSTRUMENTS, INC. D/B/A ESSEN BIOSCIENCE, INC.
Reel/Frame 048387/0249 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2017
From: WILSON, GARRETT S.; CONVERSE, CHRISTOPHER H.
To: INDEVR, INC.
Reel/Frame 043698/0274 →
MERGER Recorded Sep 26, 2017
From: VIROCYT, INC.
To: INTELLICYT CORPORATION
Reel/Frame 043699/0378 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2017
From: SMITH, BRADEN L.; ARTINGER, MICHAEL A.; KOHLMEIER, FRANCIS KEVIN
To: VIROCYT, LLC
Reel/Frame 043797/0864 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2017
From: INDEVR, INC.
To: VIROCYT, LLC
Reel/Frame 044013/0238 →
CERTIFICATE OF CONVERSION Recorded Sep 26, 2017
From: VIROCYT, LLC
To: VIROCYT, INC.
Reel/Frame 044013/0342 →
Continuity (3)
Division 15127732
Provisional Application 61969021 · Mar 21, 2014
Related Publication 20180017479A1 · Jan 18, 2018