IP Library › Granted Patent US 12,016,849
Granted Patent B2
US 12,016,849 · App. 15/730,694 · Granted Jun 25, 2024

Magnesium picolinate compositions and methods of use

Inventors: Deanna J. Nelson (Raleigh, NC); James R. Komorowski (Trumbull, CT)
Assignee: Bonafide Health, LLC
A61K31/4402A61K9/28A61K33/06A61K9/2846
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Quick Facts
Patent No.
US 12,016,849
App. No.
15/730,694
Granted
Jun 25, 2024
Kind
B2
Abstract

The present application relates to magnesium picolinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable magnesium to mammals and treating or preventing symptoms of magnesium deficiency.

Claims (15)

1. A composition comprising an effective amount of magnesium picolinate and a pharmaceutically acceptable vehicle, carrier, or diluent, wherein the effective amount increases magnesium levels in a subject in need thereof; wherein the composition comprises no more than 200 ppm of heavy metal cadmium, mercury, lead, nickel, arsenic, cobalt, antimony, thallium, barium, silver, selenium, copper, zinc, manganese, strontium, or a combination thereof.

2. The composition of claim 1 , wherein the composition is a solid composition.

3. The composition of claim 1 , wherein the composition comprises a sustained-release matrix.

4. The composition of claim 1 , wherein the composition is enteric coated.

5. The composition of claim 1 , wherein the composition comprises between about 9.05×10 −4 mg to about 905 mg of magnesium.

6. The composition of claim 1 , wherein the effective amount improves metabolic function.

7. The composition of claim 1 , wherein the effective amount improves memory.

8. The composition of claim 1 , wherein the composition comprises less than about 200 ppm of barium.

9. The composition of claim 1 , wherein the composition comprises less than about 100 ppm of barium and other heavy metals.

10. The composition of claim 1 , wherein the effective amount increases brain magnesium levels.

11. The composition of claim 1 , wherein the effective amount increases liver magnesium levels.

12. The composition of claim 1 , wherein the effective amount increases serum magnesium levels.

13. The composition of claim 1 , wherein the magnesium picolinate is safe to administer to humans without further processing.

14. The composition of claim 1 , wherein the magnesium picolinate is entirely crystalline.

15. The composition of claim 1 , wherein the composition further comprises sodium chloride.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: JDS THERAPEUTICS, LLC
To: BONAFIDE HEALTH, LLC
Reel/Frame 065072/0787 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 21, 2017
From: KOMOROWSKI, JAMES R.
To: JDS THERAPEUTICS, LLC
Reel/Frame 044193/0893 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2017
From: NELSON, DEANNA J.
To: JDS THERAPEUTICS, LLC
Reel/Frame 043842/0947 →