IP Library Granted Patent US 11,745,010
Granted Patent B2
US 11,745,010 · App. 15/733,277 · Granted Sep 5, 2023

Nerve stimulation device for current steering

Inventors: Matteo Donega (Brentford, GB); Daniel Chew (Brentford, GB); David Holder (London, GB); Kirill Aristovich (London, GB)
Assignees: GALVANI BIOELECTRONICS LIMITED; UCL BUSINESS LTD.
A61N1/0556A61N1/36053A61N1/36135A61N1/36167A61N1/3611A61N1/36114
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Quick Facts
Patent No.
US 11,745,010
App. No.
15/733,277
Granted
Sep 5, 2023
Kind
B2
Abstract

A nerve stimulation system including at least one nerve interface device is disclosed. The device includes a cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the cuff portion, each ring of electrodes including a plurality of electrodes, and wherein each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The system includes a stimulation device in communication with the pairs of electrodes to generate different electrical signals for the pairs of electrodes and a control system that causes the different signals to causes different physiological responses.

Claims (9)

1. A nerve stimulation system comprising:

at least one nerve interface device comprising:

at least one cuff portion having an assembled position in which the at least one cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway, and

a first ring of electrodes and a second ring of electrodes mounted on the at least one cuff portion, each of the first ring of electrodes and the second ring of electrodes comprising a plurality of electrodes, and wherein each electrode in the first ring of electrodes has a corresponding longitudinally-aligned electrode in the second ring of electrodes so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis,

wherein the plurality of pairs of electrodes includes at least a first pair of electrodes and a second pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion at a different circumferential position than the second pair of electrodes;

a stimulation device in electrical communication with the first pair of electrodes and the second pair of electrodes and configured to generate a first electrical signal and a second electrical signal, the first electrical signal being different from the second electrical signal with respect to at least one signal parameter selected from a group consisting of frequency, current amplitude, pulse duration, waveform shape, charge amplitude, and pulse width; and

a control system configured to cause the stimulation device to deliver the first electrical signal to the first pair of electrodes for causing a first physiological response and to deliver the second electrical signal to the second pair of electrodes for causing a second physiological response that is different from the first physiological response.

2. The nerve stimulation system of claim 1 , wherein the plurality of pairs of electrodes comprise a first subset of pairs of electrodes and a second subset of pairs of electrode, wherein one or both of the electrodes in each pair of electrodes in the first subset of pairs of electrodes has a first geometry and wherein one or both of the electrodes in each pair of electrodes in the second subset of pairs of electrodes has a second geometry different from the first geometry, further wherein the first geometry comprises a length of between 0.1 mm and 2 mm, and wherein the second geometry comprises a length of between 1 mm and 5 mm, and further wherein the length of the first geometry and the length of the second geometry extend in a direction parallel to the longitudinal axis.

3. The nerve stimulation system of claim 2 , wherein the control system is configured to cause the stimulation device to deliver the first electrical signal to a pair of electrodes in the first subset of pairs of electrodes for stimulating a myelinated fiber, and further wherein the control system is configured to cause the stimulation device to deliver the second electrical signal to a pair of electrodes in the second subset of pairs of electrodes for stimulating an unmyelinated fiber.

Assignments (3)
CHANGE OF ADDRESS Recorded Apr 16, 2025
From: GALVANI BIOELECTRONICS LIMITED
To: GALVANI BIOELECTRONICS LIMITED
Reel/Frame 070854/0393 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2023
From: CHEW, DANIEL; DONEGA, MATTEO
To: GALVANI BIOELECTRONICS LIMITED
Reel/Frame 064282/0960 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2023
From: ARISTOVICH, KIRILL; HOLDER, DAVID
To: UCL BUSINESS LTD.
Reel/Frame 064283/0012 →
Continuity (2)
Provisional Application 62609223 · Dec 21, 2017
Related Publication 20200384265A1 · Dec 10, 2020
Cited By (8)
US 12,208,268 US 12,403,313 US 12,403,315 US 12,471,831 US 12,527,956 US 12,533,520 US 12,594,424 US 12,690,801