IP Library Granted Patent US 12,257,424
Granted Patent B2
US 12,257,424 · App. 15/734,342 · Granted Mar 25, 2025

Implantable ventricular assist system and method for operating same

Inventor: Thomas Alexander Schlebusch (Renningen, DE)
Assignee: KARDION GMBH
A61M60/13A61M60/178A61M60/216A61M60/523A61M60/816A61M2205/3317A61M2205/3375
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,257,424
App. No.
15/734,342
Granted
Mar 25, 2025
Kind
B2
Abstract

The invention relates to a method for operating an implanted, ventricular assist system ( 2 ), comprising the following steps: a) determine a first impedance parameter at a first point in time by means of the assist system ( 2 ), b) determine a second impedance parameter at a second point in time by means of the assist system ( 2 ), c) at least determine a change of the impedance parameter using the first impedance parameter and the second impedance parameter, or compare at least the first or second impedance parameter to a threshold value.

Claims (36)

1. A method for operating an implantable cardiac assist system, the method comprising:

measuring an impedance parameter using one or more electrodes of the implantable cardiac assist system, the implantable cardiac assist system comprising a cannula configured to supply a fluid and a flow machine configured to generate a fluid flow, wherein the one or more electrodes are configured to measure an impedance parameter;

determining, by a processor of the implantable cardiac assist system, a first impedance parameter value of the impedance parameter at a first point in time measured by the one or more electrodes;

determining, by the processor, a second impedance parameter value of the impedance parameter at a second point in time different from the first point in time measured by the one or more electrodes; and

determining, by the processor, a change in the impedance parameter based at least in part on the first impedance parameter value and the second impedance parameter value or comparing at least the first impedance parameter value or the second impedance parameter value to a threshold value.

2. The method of claim 1 further comprising, determining a ventricular volume based at least in part on the impedance parameter.

3. The method of claim 2 , further comprising throttling the implantable cardiac assist system when the ventricular volume drops below a predetermined threshold value.

4. The method of claim 1 , wherein the first impedance parameter value and the second impedance parameter value are determined by at least two electrodes arranged on the implantable cardiac assist system.

5. The method of claim 1 , wherein determining the first impedance parameter value is performed at a first frequency and determining the second impedance parameter value is performed at a second frequency different from the first frequency.

6. The method of claim 1 further comprising determining fluid conductivity based at least in part on the first impedance parameter value and the second impedance parameter value, and wherein determining the first impedance parameter value and determining the second impedance parameter value is performed in a defined volume of the implantable cardiac assist system.

7. The method of claim 1 further comprising determining a fluid volume flow that flows through the implantable cardiac assist system.

8. The method of claim 1 further comprising determining a total fluid volume flow in a region of the implantable cardiac assist system.

9. An implantable cardiac assist system comprising:

a cannula configured to supply a fluid;

a flow machine configured to generate a fluid flow;

one or more electrodes configured to measure an impedance parameter;

a processor; and

a computer-readable storage device storing therein computer-readable instructions that, when executed by the processor, cause the processor to:

receive the impedance parameter from the one or more electrodes;

determine a first impedance parameter value of the impedance parameter at a first point in time;

determine a second impedance parameter value of the impedance parameter at a second point in time different from the first point in time; and

determine a change in the impedance parameter based at least in part on the first impedance parameter value and the second impedance parameter value, or compare at least the first impedance parameter value or the second impedance parameter value to a threshold value.

10. The system of claim 9 , wherein the processor is further configured to determine a ventricular volume based at least in part on the impedance parameter.

11. The system of claim 9 , wherein the processor is further configured to determine fluid conductivity based at least in part on the first impedance parameter value and the second impedance parameter value, and wherein determining the first impedance parameter value and determining the second impedance parameter value is performed in a defined volume of the implantable cardiac assist system.

12. The system of claim 9 , wherein the processor is configured to determine the first impedance parameter value at a first frequency, and wherein the processor is configured to determine the second impedance parameter value at a second frequency different from the first frequency.

13. An implantable cardiac assist system comprising:

a cannula configured to supply a fluid;

a flow machine configured to generate a fluid flow;

a measuring device configured to measure an impedance parameter; and

a processing unit configured to determine a first impedance parameter value of the impedance parameter at a first point in time and a second impedance parameter value of the impedance parameter at a second point in time and to determine a change in the impedance parameter based at least in part on the first impedance parameter value and the second impedance parameter value or to compare the first impedance parameter value or the second impedance parameter value to a threshold value,

wherein the measuring device comprises at least two electrodes configured to measure a ventricular impedance associated with the implantable cardiac assist system, wherein the at least two electrodes are arranged circumferentially on or in an outer surface of the implantable cardiac assist system.

14. The system of claim 13 , wherein the measuring device is configured to determine impedance at different frequencies.

15. The system of claim 13 , wherein the at least two electrodes are arranged circumferentially on an outer surface of the cannula.

16. The system of claim 13 , wherein the at least two electrodes are configured to be positioned in an area of a ventricle of a heart when the implantable cardiac assist system is implanted.

17. The system of claim 13 , further comprising a device for determining a fluid volume flow.

18. The system of claim 17 , wherein the device for determining the fluid volume flow is an ultrasonic sensor.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NO. 17055502 TO READ 17055023 PREVIOUSLY RECORDED AT REEL: 062896 FRAME: 0150. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 17, 2023
From: ROBERT BOSCH GMBH
To: KARDION GMBH
Reel/Frame 063116/0438 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2023
From: ROBERT BOSCH GMBH
To: KARDION GMBH
Reel/Frame 062896/0150 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2021
From: SCHLEBUSCH, THOMAS ALEXANDER
To: ROBERT BOSCH GMBH
Reel/Frame 058269/0214 →
SECURITY INTEREST Recorded Apr 26, 2021
From: KARDION GMBH
To: EDWARDS LIFESCIENCES HOLDING, INC.
Reel/Frame 056046/0422 →
Cited By (9)
US 1,092,716 US 12,478,267 US 12,491,357 US 12,502,524 US 12,508,418 US 12,569,671 US 12,667,714 US 12,702,816 US 12,702,821