IP Library Granted Patent US 12,178,554
Granted Patent B2
US 12,178,554 · App. 15/734,519 · Granted Dec 31, 2024

Systems and methods for determining a viscosity of a fluid

Inventors: Ingo Stotz (Ditzingen, DE); Thomas Alexander Schlebusch (Renningen, DE)
Assignee: KARDION GMBH
A61B5/02035A61B5/0215A61B5/7246A61B8/488A61M60/178A61M60/216A61M60/403A61M60/523A61M60/531A61M2205/3331A61M2205/3365A61M2205/3375A61M2205/3379
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Quick Facts
Patent No.
US 12,178,554
App. No.
15/734,519
Granted
Dec 31, 2024
Kind
B2
Abstract

The approach presented here relates to a determination appliance ( 100 ) for determining a viscosity of a fluid. The determination appliance ( 100 ) has at least one determination device ( 110 ) and a provisioning device ( 115 ). The determination device ( 110 ) is designed to determine the viscosity of the fluid and/or a rotational speed (ω) of a blade wheel ( 205 ) for conveying the fluid by using at least one detected volume flow of the fluid and a detected pressure difference of the fluid. The provisioning device ( 115 ) is designed to provide or send a viscosity signal ( 130 ) representing the viscosity determined by the determination device ( 110 ).

Claims (38)

1. A ventricular assist system comprising:

an impeller;

a drive device coupled to the impeller, the drive device configured to drive the impeller at a rotational speed (ω);

a pressure sensor device; and

a determination device comprising:

a cannula configured to be implanted in a body of a patient, wherein the cannula comprises:

a lateral receiving interface distal to the impeller, configured to receive blood of the patient into an interior of the cannula; and

an outlet interface, wherein the impeller is configured to convey the blood from the lateral receiving interface to the outlet interface; and

a volumetric flow sensor positioned at a tip of the cannula distal to the impeller and configured to sense a volumetric flow (Q) of the blood of the patient through the cannula, the volumetric flow sensor comprising a Doppler ultrasonic sensor;

wherein the pressure sensor device is configured to sense a pressure difference (Δp) of the blood in a region of the receiving interface and a region of the outlet interface, and

wherein the determination device is configured to determine viscosity (η) of blood in the body of the patient based on at least the sensed volumetric flow (Q) of the blood, the sensed pressure difference (Δp) of the blood, and either the rotational speed (ω) of the impeller or an electric power input P el of a drive device for the impeller.

2. The ventricular assist system of claim 1 , wherein the determination device is configured to determine the viscosity (η) based on a functional relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η).

3. The ventricular assist system of claim 1 , wherein the determination device is configured to determine the viscosity (η) using a lookup table.

4. The ventricular assist system of claim 3 , wherein a relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η) is stored in the lookup table.

5. The ventricular assist system of claim 1 , wherein the impeller is positioned in a region of the outlet interface.

6. The ventricular assist system of claim 1 , wherein the pressure sensor device comprises at least one differential pressure sensor or two barometric pressure sensors, wherein the at least one differential pressure sensor or two barometric pressure sensors are configured to measure the pressure difference (Δp) between two sensor points.

7. The ventricular assist system of claim 1 , wherein the pressure sensor device is configured to sense the pressure difference (Δp) between two sensor points.

8. A method for determining a viscosity (η) of blood of a patient in a ventricular assist system, comprising:

sensing a volumetric flow (Q) using a volumetric flow sensor of a determination device of the ventricular assist system, the volumetric flow sensor comprising a Doppler ultrasonic sensor arranged in a distal tip of a cannula of the determination device, the cannula, configured to be implanted in a body of the patient, wherein the ventricular assist system comprises:

an impeller configured to convey blood from a lateral receiving interface of the cannula distal to the impeller to an outlet interface of the cannula; and

a drive device coupled to the impeller, the drive device configured to drive the impeller at a rotational speed (ω);

sensing a pressure difference (Δp) of blood in a region of the receiving interface and the outlet interface; and

determining the viscosity (η) of the blood based on at least the sensed volumetric flow (Q) of the blood, the sensed pressure difference (Δp) of the blood, and either the rotational speed (ω) of the impeller or an electric power input P el of a drive device for the impeller.

9. The method of claim 8 , wherein determining the viscosity (η) comprises determining the viscosity (η) based on a functional relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η).

10. The method of claim 8 , wherein determining the viscosity (η) comprises using a lookup table.

11. The method of claim 10 , wherein a relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η) is stored in the lookup table.

12. The method of claim 8 , wherein the impeller is positioned in a region of the outlet interface.

13. The method of claim 8 , wherein the pressure sensor device comprises at least one differential pressure sensor or two barometric pressure sensors.

14. The method of claim 8 , wherein the pressure sensor device is configured to sense a pressure difference (Δp) between two sensor points.

15. A non-transitory computer-readable storage medium comprising instructions that, when executed, direct a processor to perform a method comprising:

sensing a volumetric flow (Q) using a volumetric flow sensor of a determination device of a ventricular assist system, the volumetric flow sensor comprising a Doppler ultrasonic sensor arranged in a distal tip of a cannula of the determination device, the cannula, configured to be implanted in a body of a patient, wherein the ventricular assist system comprises:

an impeller configured to convey blood from a lateral receiving interface of the cannula that is distal to the impeller to an outlet interface of the cannula; and

a drive device coupled to the impeller, the drive device configured to drive the impeller at a rotational speed (ω);

sensing a pressure difference (Δp) of blood in a region of the receiving interface and the outlet interface; and

determining a viscosity (η) of the blood based on at least the sensed volumetric flow (Q) of the blood, the sensed pressure difference (Δp) of the blood, and either the rotational speed (co) of the impeller or an electric power input P el of a drive device for the impeller.

16. The non-transitory computer-readable storage medium of claim 15 , wherein determining the viscosity (η) comprises determining the viscosity (η) based on a functional relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η).

17. The non-transitory computer-readable storage medium of claim 15 , wherein determining the viscosity (η) comprises using a lookup table.

18. The non-transitory computer-readable storage medium of claim 17 , wherein a relationship between the volumetric flow (Q), the pressure difference (Δp), and the viscosity (η) is stored in the lookup table.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2022
From: ROBERT BOSCH GMBH
To: KARDION GMBH
Reel/Frame 058730/0375 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2022
From: STOTZ, INGO; SCHLEBUSCH, THOMAS ALEXANDER
To: ROBERT BOSCH GMBH
Reel/Frame 058712/0213 →
SECURITY INTEREST Recorded Apr 26, 2021
From: KARDION GMBH
To: EDWARDS LIFESCIENCES HOLDING, INC.
Reel/Frame 056046/0422 →
Priority Claims (1)
DE 102018208936.1 · Jun 6, 2018 · national
Continuity (1)
Related Publication 20220047173A1 · Feb 17, 2022
Cited By (10)
US 12,311,160 US 12,377,256 US 12,478,267 US 12,491,357 US 12,502,524 US 12,508,418 US 12,569,671 US 12,667,714 US 12,702,816 US 12,702,821