Devices, methods, and systems for priming, separating, and collecting blood components

1. A method of operating a blood processing system, wherein said blood processing system comprises a deck and a disposable kit, wherein said deck comprises a pressure transducer, wherein at least part of said kit is installed on said deck, wherein said at least part of said kit comprises a pressure dome positioned on said pressure transducer, and wherein said pressure dome comprises a flow chamber, a first flow port for said flow chamber, and a second flow port for said flow chamber, said method comprising:

executing a first negative pressure test on said pressure dome and comprising attempting to generate a first vacuum within said flow chamber by withdrawing fluid out of said flow chamber through one of said first and second flow ports;

executing a first positive pressure test on said pressure dome comprising attempting to generate a first positive pressure within said flow chamber by directing fluid into said flow chamber through one of said first and second flow ports, wherein said first positive pressure test is executed after said first negative pressure test; and

executing a second negative pressure test on said pressure dome comprising attempting to generate a second vacuum within said flow chamber by withdrawing fluid out of said flow chamber through one of said first and second flow ports, wherein said second negative pressure test is executed after said first negative pressure test, and wherein said second vacuum is larger than said first vacuum; and

wherein said first negative pressure test, said first positive pressure test, and said second negative pressure test are each executed by said blood processing system.

2. The method of claim 1 , further comprising:

executing a first assessing step comprising assessing an installation of said pressure dome on said pressure transducer using said first negative pressure test, wherein said first assessing step is executed by said blood processing system.

3. The method of claim 2 , wherein said blood processing system further comprises a display, said method further comprising said blood processing system providing an indication on said display if said first assessing step determines that said pressure dome failed to pass said first negative pressure test.

4. The method of claim 2 , wherein said first assessing step comprises a first determining step, which in turn comprises determining if a pressure within said flow chamber satisfies a first negative pressure threshold.

5. The method of claim 4 , wherein said first determining step comprises using an output of said pressure transducer during said first negative pressure test.

6. The method of claim 4 , wherein satisfying said first negative pressure threshold comprises at least one of said pressure within said flow chamber being between a first negative pressure and a second negative pressure and said first negative pressure threshold comprises said pressure within said flow chamber being of at least a first predetermined amount of vacuum.

7. The method of claim 6 , wherein said first predetermined vacuum is within a range of about −20 mmHg to about −40 mmHG.

8. The method of claim 1 , wherein if said pressure dome does not pass said first negative pressure test, said method further comprises:

reinstalling said pressure dome on said pressure transducer; and

repeating said first negative pressure test.

9. The method of claim 1 , wherein each of said first positive pressure test and said second negative pressure test are executed by said blood processing system only if said blood processing system determines that said pressure dome passed said first negative pressure test.

10. The method of claim 1 , further comprising:

executing a second assessing step comprising assessing an operational range of said pressure transducer using said each of said first positive pressure test and said second negative pressure test.

11. The method of claim 10 , wherein said blood processing system further comprises a display, said method further comprising said blood processing system providing an indication on said display if said second assessing step determines that said pressure dome failed to pass at least one of said first positive pressure test and said second negative pressure test.

12. The method of claim 10 , wherein said second assessing step comprises a second determining step, which in turn comprises determining if a pressure within said flow chamber satisfies a first positive pressure threshold for said first positive pressure test.

13. The method of claim 12 , wherein said second determining step comprises using an output of said pressure transducer during said first positive pressure test.

14. The method of claim 12 , wherein satisfying said first positive pressure threshold comprises at least one of said pressure within said flow chamber being between a first positive pressure and a second positive pressure and said pressure within said flow chamber being of at least a first predetermined amount.

15. The method of claim 12 , wherein satisfying said first positive pressure threshold comprises said pressure within said flow chamber being at least 330 mmHG.

16. The method of claim 10 , wherein said second assessing step further comprises a third determining step, which in turn comprises determining if a pressure within said flow chamber satisfies a second negative pressure threshold for said second negative pressure test.

17. The method of claim 16 , wherein said third determining step comprises using an output of said pressure transducer during said second negative pressure test.

18. The method of claim 16 , wherein satisfying said second negative pressure threshold comprises at least one of said pressure within said flow chamber being between a third negative pressure and a fourth positive pressure and said pressure within said flow chamber being of at least a second predetermined amount of vacuum.

19. The method of claim 16 , wherein satisfying said second negative pressure threshold comprises said pressure within said flow chamber being at a minimum vacuum level of −300 mmHG.

20. The method of claim 1 , wherein said first positive pressure test and said second negative pressure test are executable in any order.

21. The method of claim 1 , wherein said second vacuum is larger than said first vacuum.

22. The method of claim 1 , wherein said pressure dome comprises a flexible diaphragm, wherein an amount of force that said flexible diaphragm exerts on said pressure transducer should change for each of said first negative pressure test, said first positive pressure test, and said second negative pressure test.

23. A method for verifying installation of a pressure dome in a centrifuge system, comprising:

applying a vacuum to a pressure sensor dome at an inlet of a centrifuge using a pump;

determining whether the pump evacuated a volume of air from an area under the pressure sensor dome;

determining a pressure within the pressure sensor dome; and

generating an alert based upon one of: the evacuated volume of air and the determined pressure.

24. The method of claim 23 , wherein upon the volume of air exceeding a threshold amount, the alert corresponds to an indication that the pressure dome is not correctly installed.

25. The method of claim 23 , wherein upon the volume of air not exceeding a threshold volume and the pressure being above a threshold amount, the vacuum continues to be applied.

26. The method of claim 23 , wherein upon pressure being below a threshold amount, the alert corresponds to the pressure dome is installed correctly.