Assistance device and method for an interventional hemodynamic measurement
The invention relates to an assistance device, an assistance system and an assistance method for assisting a practitioner in an interventional hemodynamic (e.g fractional flow reserve (FFR)) measurement on a subject. The FFR pressure measurements are combined with an, for example, angiography-based assessment of the coronary vessel geometry. An advanced computational fluid dynamics model may be employed to add flow and myocardial resistance data based on the interventional pressure values and on a vascular model generated prior to the intervention. In case that these data are available prior to the intervention, the location of most optimal positions for pressure measurements can be pre-calculated and by overlay of the vessel tree, for example, on the X-ray projection, advice can be given for the interventional cardiologist during the intervention.
1. An assistance device for assisting a practitioner in an interventional hemodynamic measurement on a subject, comprising:
a memory that stores a plurality of instructions; and
processor circuitry that couples to the memory and that is configured to execute the plurality of instructions to:
acquire a vessel tree model of vessel geometry of the subject;
determine a set of positions in a vessel tree for the interventional hemodynamic measurement based on the vessel tree model complying with a predetermined metric, each position in the set of positions for the interventional hemodynamic measurement is a hemodynamic parameter measurement position that indicates where at least one hemodynamic parameter is to be measured, wherein the vessel tree includes a main vessel; a branching point connected to the main vessel; a first vessel branch connected to the main vessel via the branching point; and a second vessel branch connected to the main vessel via the branching point; and
cause a display to simultaneously display:
the main vessel of the vessel tree, the branching point of the vessel tree the first vessel branch of the vessel tree and the second vessel branch of the vessel tree;
at one of the main vessel, the branching point, the first vessel branch, and the second vessel branch, a first hemodynamic parameter measurement position of the hemodynamic parameter measurement positions; and
at another of the main vessel, the branching point, the first vessel branch, and the second vessel branch a second hemodynamic parameter measurement position of the hemodynamic parameter measurement positions.
2. The assistance device according to claim 1 , wherein the processor circuitry is further configured to provide a plurality of simulations using a lumped parameter model for computational fluid dynamics and the metric includes a stability of a solution including a set of positions.
3. The assistance device according to claim 2 , wherein the processor circuitry is further configured to obtain the stability of a solution by providing simulated pressure variations and/or flow variations at a plurality of positions in the vessel tree model.
4. The assistance device according to claim 1 , wherein the processor circuitry is further configured to take into account information on a position and/or degree of a stenosis in the vessel of the subject.
5. The assistance device according to claim 1 , wherein the predetermined metric includes a plurality of positions included in the hemodynamic parameter measurement positions.
6. The assistance device according to claim 1 , wherein the processor circuitry is further configured to determine temporal information for at least one of the hemodynamic parameter measurement positions, the temporal information indicating a measurement time in relation to a predetermined reference.
7. The assistance device according to claim 6 , wherein the predetermined reference is a cardiac phase of the subject.
8. The assistance device according to claim 1 , wherein the processor circuitry is further configured to receive three-dimensional image data and/or a plurality of two-dimensional image data of the vessel geometry of the subject and to generate the vessel tree model based on the image data.
9. The assistance device according to claim 8 , wherein the processor circuitry is further configured to receive a pre-interventional data set of the vessel geometry of the subject and to segment the data set for generating the vessel tree model.
10. The assistance device according to claim 1 , wherein the vessel tree model is a lumen and centerline model.
11. The assistance device according to claim 1 , wherein the processor circuitry is further configured to register the vessel tree model with one or more invasive angiograms and to cause the display to display the hemodynamic parameter measurement positions in an overlay onto a projection during intervention.
12. An assistance system for assisting a practitioner in an interventional hemodynamic measurement on a subject, comprising:
the assistance device according to claim 1 and at least one of
a data storage device storing image data of vessel geometry of the subject and
the display, wherein the display is configured to display the hemodynamic parameter measurement positions to the practitioner.
13. An assistance method for assisting a practitioner in an interventional hemodynamic measurement on a subject, comprising:
acquiring a vessel tree model of vessel geometry of the subject;
determining a set of positions in a vessel tree for the interventional hemodynamic measurement based on the vessel tree model complying with a predetermined metric, each position in the set of positions for the interventional hemodynamic measurement is a hemodynamic parameter measurement position that indicates where at least one hemodynamic parameter is to be measured, wherein the vessel tree includes: a main vessel; a branching point connected to the main vessel; a first vessel branch connected to the main vessel via the branching point; and a second vessel branch connected to the main vessel via the branching point; and
causing a display to simultaneously display:
the main vessel of the vessel tree, the branching point of the vessel tree, the first vessel branch of the vessel tree and the second vessel branch of the vessel tree;
at one of the main vessel, the branching point, the first vessel branch, and the second vessel branch, a first hemodynamic parameter measurement position of the hemodynamic parameter measurement positions; and
at another of the main vessel, the branching point the first vessel branch, and the second vessel branch, a second hemodynamic parameter measurement position of the hemodynamic parameter measurement positions.
14. A non-transitory computer-readable medium having one or more executable instructions stored thereon which, when executed by at least one processor, cause the at least one processor to perform an assistance method for assisting a practitioner in an interventional hemodynamic measurement on a subject, comprising:
acquiring a vessel tree model of vessel geometry of the subject;
determining a set of positions in a vessel tree for the interventional hemodynamic measurement based on the vessel tree model complying with a predetermined metric, each position in the set of positions for the interventional hemodynamic measurement is a hemodynamic parameter measurement position that indicates where at least one hemodynamic parameter is to be measured, wherein the vessel tree includes: a main vessel; a branching point connected to the main vessel; a first vessel branch connected to the main vessel via the branching point; and a second vessel branch connected to the main vessel via the branching point; and
causing a display to simultaneously display:
the main vessel of the vessel tree, the branching point of the vessel tree, the first vessel branch of the vessel tree, and the second vessel branch of the vessel tree;
at one of the main vessel, the branching point, the first vessel branch, and the second vessel branch, a first hemodynamic parameter measurement position of the hemodynamic parameter measurement positions; and
at another of the main vessel, the branching point, the first vessel branch, and the second vessel branch, a second hemodynamic parameter measurement position of the hemodynamic parameter measurement positions.