IP Library Granted Patent US 11,045,483
Granted Patent B2
US 11,045,483 · App. 15/749,348 · Granted Jun 29, 2021

Pain-killing composition comprising a salicylic acid derivative

Inventor: Rene Chelle (Deyme, FR)
Assignee: AB7 INNOVATION S.A.S.U.
A61K31/618A01K13/003A61K9/0017A61K31/35A61K31/352A61K36/23A61K36/45A61K36/53A61K36/534A61K36/899A61K47/32A61K47/34A61P19/02A61P29/00
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Quick Facts
Patent No.
US 11,045,483
App. No.
15/749,348
Granted
Jun 29, 2021
Kind
B2
Abstract

The subject-matter of the present invention is the use of a therapeutic composition comprising, in an applying carrier, at least one essential oil for relieving muscle and/or joint pain in an animal subject, wherein said composition topically treats an area of the skin of said subject, characterized in that said composition comprises methyl salicylate, which constitutes, with at least one essential oil of the composition containing same in only a small amount or not at all, an active agent within which the rate of transport of the methyl salicylate through the skin is increased by virtue of the oil, which is an essential oil.

Claims (9)

1. Therapeutic monoblock device comprising a polymer matrix topical application carrier and an active agent for inducing relieving muscle and/or joint pain in a human or animal subject, the monoblock device being free of an adhesive layer, said active agent comprising methyl salicylate provided by wintergreen essential oil, and an auxiliary essential oil, wherein the active agent is incorporated in the polymer matrix, wherein the polymer matrix is a copolymer of ethylene and vinyl acetate (EVA), whose vinyl acetate content is between 15 and 60% by weight, and the polymer matrix represents 80 to 90% by weight of the device, and the active agent comprises 52 to 85% by weight of methyl salicylate, the rate of transport of the methyl salicylate through the skin being increased by virtue of the auxiliary essential oil.

2. Therapeutic monoblock device according to claim 1 , wherein the auxiliary essential oil of the active agent constitutes between 15 and 48% by weight of the active agent.

3. Therapeutic monoblock device according to claim 1 , wherein the auxiliary essential oil of the active agent is rosemary essential oil ( Rosmarinus officinalis ), peppermint essential oil, Ceylan citronella essential oil, coriander essential oil, or a combination thereof.

4. Therapeutic monoblock device according to claim 3 , wherein the auxiliary essential oil contains at least one monoterpene alcohol chosen from the group formed by 1,8-cineole, menthol, geraniol and linalool.

5. Therapeutic monoblock device according to claim 1 , wherein the essential wintergreen oil constitutes between 1 and 15% by weight of the total essential oil content of the device.

6. Therapeutic monoblock device according to claim 1 , wherein the auxiliary essential oil constitutes from 0.15 to 9% by weight of the device.

7. Therapeutic monoblock device according to claim 1 , wherein the active agent further comprises at least one formulation additive chosen from a vegetable oil, an inert filler of mineral origin, a dye, a surfactant, a synthetic perfume, a natural perfume, or a mixture thereof.

8. Therapeutic monoblock device according to claim 7 , wherein said inert filler of mineral origin is a powder.

9. A method of topically inducing arthritic pain relief comprising applying the therapeutic monoblock device of claim 1 against the skin of a human or animal subject to be treated for a sufficient time to enable the pain relief.

Assignments (4)
MERGER Recorded Mar 24, 2023
From: AB7 INNOVATION SASU
To: AB7 SANTE
Reel/Frame 063088/0287 →
SECURITY INTEREST Recorded Jun 30, 2021
From: EXELA HOLDINGS, INC.; EXELA PHARMA SCIENCES, LLC; EXELA PHARMSCI, INC.; EXELA STERILE MEDICINES LLC; EXELA STERILE PRODUCTS LLC; EXELA STERILE EQUIPMENT, LLC; EXELA ADVANCED STRATEGIES LLC; AGELEX, LLC; EXELA HEALTH SYSTEMS, LLC; EXELA INITIATIVES, LLC; EXELA INNOVATIONS, LLC
To: LIVE OAK BANKING COMPANY
Reel/Frame 056722/0188 →
SECURITY INTEREST Recorded Jun 30, 2021
From: EXELA HOLDINGS, INC.; EXELA PHARMA SCIENCES, LLC; EXELA PHARMSCI, INC.; EXELA STERILE MEDICINES LLC; EXELA STERILE PRODUCTS LLC; EXELA STERILE EQUIPMENT, LLC; EXELA ADVANCED STRATEGIES LLC; AGELEX, LLC; EXELA HEALTH SYSTEMS, LLC; EXELA INITIATIVES, LLC; EXELA INNOVATIONS, LLC
To: LIVE OAK BANKING COMPANY
Reel/Frame 056722/0250 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2018
From: CHELLE, RENE
To: AB7 INNOVATION S.A.S.U.
Reel/Frame 045106/0938 →
Priority Claims (1)
FR FR1501724 · Aug 12, 2015 · national
Continuity (1)
Related Publication 20180221392A1 · Aug 9, 2018