IP Library Granted Patent US 10,568,887
Granted Patent B2
US 10,568,887 · App. 15/750,151 · Granted Feb 25, 2020

Combination therapies for treatment of cancer

Inventors: David J. Bearss (Alpine, UT); Steven L. Warner (Sandy, UT); Adam Siddiqui-Jain (South Jordan, UT); Clifford J. Whatcott (West Jordan, UT); Wontak Kim (Lehi, UT)
Assignee: Tolero Pharmaceuticals, Inc.
A61K31/519A61K31/445A61K31/4433A61K31/453A61K31/706A61K45/06A61P35/02A61K2300/00
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Quick Facts
Patent No.
US 10,568,887
App. No.
15/750,151
Granted
Feb 25, 2020
Kind
B2
Abstract

Combination therapies for treatment of cancer are provided. The disclosed methods comprise administration of a cyclin-dependent kinase inhibitor and a DNA methyltransferase inhibitor to a mammal in need thereof.

Claims (1)

1. A method of treating myelodysplastic syndrome (MDS) comprising administering a therapeutically effective amount of decitabine and subsequently a therapeutically effective amount of alvocidib to a human in need thereof.

Assignments (4)
CHANGE OF NAME Recorded Apr 27, 2022
From: SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC.
To: SUMITOMO PHARMA ONCOLOGY, INC.
Reel/Frame 059809/0557 →
MERGER Recorded Jul 10, 2020
From: TOLERO PHARMACEUTICALS, INC.
To: BOSTON BIOMEDICAL, INC.
Reel/Frame 053181/0114 →
CHANGE OF NAME Recorded Jul 10, 2020
From: BOSTON BIOMEDICAL, INC.
To: SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC.
Reel/Frame 053181/0133 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2018
From: BEARSS, DAVID J.; WARNER, STEVEN L.; SIDDIQUI-JAIN, ADAM; WHATCOTT, CLIFFORD J.; KIM, WONTAK
To: TOLERO PHARMACEUTICALS, INC.
Reel/Frame 045626/0176 →
Continuity (2)
Provisional Application 62200499 · Aug 3, 2015
Related Publication 20180256580A1 · Sep 13, 2018
Cited By (1)
US 12,338,261