Granted Patent
B2
US 10,377,764 · App. 15/753,361 · Granted Aug 13, 2019
Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
Inventors:
Stephen Joseph Shuttleworth (Oxfordshire, GB); Franck Alexandre Silva (Oxfordshire, GB); Alexander Richard Liam Cecil (Oxfordshire, GB); Alice Elizabeth Gatland (Oxfordshire, GB); Daniel John Finnemore (Oxfordshire, GB)
Assignee:
Karus Therapeutics Limited
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Abstract
The invention relates to a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein each R 3 is independently selected from H, halo, fluorinated C 1 -C 10 alkyl, —I—C 1 -C 10 alkyl, —NH—C 1 -C 10 alkyl, —S—C 1 -C 10 alkyl, —O-fluorinated C 1 -C 10 alkyl, —NH-acyl, —NH—C(O)—NH-alkyl, —C—(O)—NH-alkyl, with the proviso that at least one of R 3 is not H.
Claims (4)
1. A compound represented by:
or
a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound according to claim 1 , and a pharmaceutically acceptable excipient.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 5, 2022
From: KARUS THERAPEUTICS LIMITED
To: CONVALIFE (SHANGHAI) CO. LIMITED
Reel/Frame 061315/0660 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 25, 2019
From: SHUTTLEWORTH, STEPHEN JOSEPH; SILVA, FRANCK ALEXANDRE; CECIL, ALEXANDER RICHARD LIAM; GATLAND, ALICE ELIZABETH; FINNEMORE, DANIEL JOHN
To: KARUS THERAPEUTICS LIMITED
Reel/Frame 049579/0029 →
Priority Claims (1)
GB 1514751.5
· Aug 19, 2015
· national
Continuity (1)
Cited By (2)