IP Library Granted Patent US 10,625,210
Granted Patent B2
US 10,625,210 · App. 15/769,461 · Granted Apr 21, 2020

Mixing method and system

Inventors: Klaus Gebauer (Uppsala, SE); Partha Sarathy Doddapadam Srinivasa Raghavachar (Bangalore, IN); Narendra G R (Bangalore, IN); Nachiket Karmarkar (Bangalore, IN); Ajit S. Vernekar (Bangalore, IN); Prashanth Hosabettu Mohan (Bangalore, IN); Sasi Kumar Nutalapati (Bangalore, IN)
Assignee: GE Healthcare Bio-Sciences AB
B01D61/20B01F5/10B01F5/102B01F15/0085B01F15/00136B01F15/00253B01D2311/25B01D2313/083B01D2315/16
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Quick Facts
Patent No.
US 10,625,210
App. No.
15/769,461
Granted
Apr 21, 2020
Kind
B2
Abstract

A method and a system for improving mixing of content in a container 3 provided in a filter system 1, said method comprising providing a mixing loop 13 parallel to a recirculation flow path 11 of the filter system 1.

Claims (14)

1. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of operational conditions of a feed pump arranged to supply content from the container to the filter and further comprising the steps of:

switching the mixing pump on when the feed pump pumps feed to the filter at a flow rate below a predefined threshold rate; and/or

switching the mixing pump off when the feed pump pumps feed to the filter at a flow rate above a predefined threshold rate.

2. The method according to claim 1 , further comprising controlling a mixing pump provided in the mixing loop in dependence of properties of content in the system and/or conditions in the system.

3. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of sensor responses from at least two sensors provided at different locations in the system, said sensors measuring the same property of the content in the container.

4. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of fluid flow into the container provided from an additional pump and fluid line separate from the recirculation flow path.

5. A filter system comprising a container with a content connected to a filter by a recirculation flow path, wherein the filter system further comprises a mixing loop in connection with the container, said mixing loop being provided in parallel with the recirculation flow path, and further comprising a control system arranged to control a mixing pump provided in the mixing loop in dependence of sensor responses from at least two sensors provided at different locations in the system and measuring the same property of the content in the container.

6. The filter system according to claim 5 , further comprising a control system arranged to control a mixing pump provided in the mixing loop in dependence of properties of content in the system and/or conditions in the system.

7. The filter system according to claim 5 , wherein the control system is further in dependence of operational conditions of a feed pump provided in the recirculation flow path.

8. The filter system according to claim 7 , wherein said filter system comprises the container with a content, the filter connected by the recirculation flow path to a recirculation inlet and a recirculation outlet of the container and a feed pump provided in the recirculation flow path pumping content of the container to the filter, wherein the filter system further comprises the mixing loop parallel to the recirculation flow path, said mixing loop comprising a mixing pump and is connected to a mixing inlet and a mixing outlet of the container and said filter system comprising the control system which can communicate with both the mixing pump and the feed pump.

9. A filter system comprising a container with a content connected to a filter by a recirculation flow path, wherein the filter system further comprises a mixing loop in connection with the container, said mixing loop being provided in parallel with the recirculation flow path,

wherein the filter system further comprises a control system arranged to control a mixing pump provided in the mixing loop in dependence of operational conditions of a feed pump provided in the recirculation flow path and the container with a content, the filter connected by the recirculation flow path to a recirculation inlet and a recirculation outlet of the container and a feed pump provided in the recirculation flow path pumping content of the container to the filter, wherein said mixing loop comprising the mixing pump is connected to a mixing inlet and a mixing outlet of the container, and said filter system comprising the control system can communicate with both the mixing pump and the feed pump; and

wherein the control system further is arranged to control the mixing pump to be switched on when the feed pump pumps feed to the filter at a flow rate below a predefined threshold rate and/or control the mixing pump to be switched off when the feed pump pumps feed to the filter at a flow rate above a predefined threshold rate.

10. The filter system according to claim 5 , wherein the container is a hanging bag.

Assignments (2)
CHANGE OF NAME Recorded Oct 5, 2020
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 054262/0184 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 19, 2018
From: GEBAUER, KLAUS; DODDAPADAM SRINIVASA RAGHAVACHAR, PARTHA SARATHY; G R, NARENDRA; KARMARKAR, NACHIKET; VERNEKAR, AJIT S.; MOHAN, PRASHANTH HOSABETTU; NUTALAPATI, SASI KUMAR
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 045587/0720 →