IP Library Granted Patent US 11,021,505
Granted Patent B2
US 11,021,505 · App. 15/774,754 · Granted Jun 1, 2021

Aqueous extract enriched with small RNAs and compositions comprising such extracts and to their cosmetic uses

Inventors: Elodie Oger (Vallauris, FR); Valerie Lequoy (Valbonne, FR); Frederique Portolan (Valbonne, FR)
Assignee: ISP INVESTMENTS LLC
C07H1/08A61K8/44A61K8/606A61K8/9789A61K8/9794A61Q17/04A61Q19/00A61Q19/007A61Q19/08C07H21/02C12N15/1003C12N15/1017A61K2800/10A61K2800/30A61K2800/805
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Quick Facts
Patent No.
US 11,021,505
App. No.
15/774,754
Granted
Jun 1, 2021
Kind
B2
Abstract

The invention relates to an aqueous extract enriched with small RNA having a maximum length of 150 nucleotides, from plant material. The invention relates to an aqueous extract of plant material, enriched with small RNAs having a maximum length of 150 nucleotides, which can be obtained by such a method, as well as to the compositions comprising such an extract and to their cosmetic uses for combating the signs of skin aging and for improving the hydration of the skin.

Claims (5)

1. An aqueous extract of plant material, enriched with small RNA having a maximum length of 150 nucleotides, wherein the extract comprises, by weight relative to the total weight of the extract, 5-60 g/kg of dry extract and 10-1000 mg/kg of small RNAs having a maximum length of 150 nucleotides, 0.5 to 30 g/kg of protein fragments and 0.5 to 50 g/kg of sugars, and comprises no DNA.

2. The extract according to claim 1 , wherein the extract is diluted in a solvent and comprises, by weight relative to the total weight of the extract, 5-35 g/kg of dry extract, 0.5-20 g/kg of protein fragments, 0.5-30 g/kg of sugars, and 10-500 mg/kg of small RNA having a maximum length of 150 nucleotides.

3. A composition comprising an effective quantity of the extract of claim 1 , as an anti-aging active agent, and a physiologically acceptable medium.

4. The composition according to claim 3 , wherein the extract is present at a concentration between 1 and 5% by weight of the total weight of the composition.

5. The composition according to claim 3 , wherein the composition is formulated for being applied topically to the skin.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jan 10, 2020
From: THE BANK OF NOVA SCOTIA
To: HERCULES LLC; ISP INVESTMENTS LLC
Reel/Frame 051561/0676 →
SUPPLEMENTAL SECURITY AGREEMENT Recorded May 24, 2019
From: HERCULES LLC; ISP INVESTMENTS LLC
To: THE BANK OF NOVA SCOTIA
Reel/Frame 049286/0434 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2018
From: OGER, ELODIE; LEQUOY, VALERIE; PORTOLAN, FREDERIQUE
To: ISP INVESTMENTS LLC
Reel/Frame 046887/0228 →
Priority Claims (1)
FR 1502361 · Nov 17, 2015 · national
Continuity (1)
Related Publication 20180371000A1 · Dec 27, 2018