Polymeric film comprising vibration dampening and barrier properties
View Patent ↗The presently disclosed subject matter is directed generally to multilayer films suitable for use in forming pouches, such as (but not limited to) bioprocessing pouches. When used in the formation of solution pouches, the disclosed films help prevent or reduce the number of seal failures, such as during transportation or use. The disclosed films comprise first and second vibration dampening layers and first and second barrier layers.
1. A 2D or 3D pouch comprising front and back sheets oriented in a face-to-face relationship and sealed to each other along adjacent side edges to define an interior compartment therebetween, the pouch being formed from a polymeric film comprising:
a. a first vibration dampening layer;
b. a second vibration dampening layer;
c. first and second barrier layers;
d. a skin layer; and
e. a sealant layer comprising:
ii. about 20-50 weight percent lock down sealant having a seal strength of at least 16 pound force in accordance with ASTM F88;
ii. about 20-50 weight percent metallocene plastomer with melt index in accordance with ASTM D1238≥1.0 and density of less than 0.92; and
iii. about 10-30 weight percent cyclic olefin polymer;
wherein the vibration dampening layers have a peak tan delta of at least 0.20 at −45° C. to −15° C. in accordance with ASTM D4065.
2. The pouch of claim 1 , wherein the first barrier layer comprises EVOH with 30-48 mole percent ethylene and the second barrier layer comprises EVOH with less than 39 mole percent ethylene.
3. The pouch of claim 1 , wherein the film is a multilayer film and said first and second dampening layers are inner film layers.
4. The pouch of claim 1 , wherein the layer is positioned adjacent or directly adjacent to an outer film layer.
5. The pouch of claim 1 , wherein the film exhibits Young's modulus of about 10,000 to 60,000 pounds/square inch in accordance with ASTM D882.
6. The pouch of claim 1 , wherein the film is substantially free of surface-modifying additives and does not inhibit the growth of cell culture.
7. The pouch of claim 1 , wherein the film exhibits an oxygen transmission rate of less than 200 cc at 100% relative humidity and 73° F.
8. The pouch of claim 1 , wherein the film exhibits an oxygen transmission rate of less than 10 cc at 50% ouU100% in relative humidity and 73° F.
9. The pouch of claim 1 , wherein the film exhibits an oxygen transmission rate of less than 10 cc at 0% relative humidity and 73° F.
10. The pouch of claim 1 , wherein at least one vibration dampening layer comprises about 25% of the total film thickness.
11. The pouch of claim 1 , wherein the vibration dampening layers comprise alpha olefin polymer blended with an acrylate polymer, a styrenic block copolymer, or a modified or grafted acrylate polymer.
12. The pouch of claim 1 , wherein the skin layer comprises PET, polyamide, polyethylene, or combinations thereof.
13. The pouch of claim 1 , further comprising a solution contained within the interior pouch compartment.
14. The pouch of claim 13 , wherein the solution is selected from the group comprising: water, saline solution, buffer solution, Ringer solution, dextrose solution, Hank solution, glucose solution, and combinations thereof.