IP Library Granted Patent US 9,974,750
Granted Patent B1
US 9,974,750 · App. 15/785,277 · Granted May 22, 2018

Synthesis of ifflaionic acid nanoparticles

Inventors: Shaza Mohamed Adel Al-Massarani (Riyadh, SA); Rabab Abd El Moneim Khalil El Dib (Riyadh, SA); Ali Ali El-Gamal (Riyadh, SA); Manal Ahmed Gasmelseed (Riyadh, SA)
Assignee: KING SAUD UNIVERSITY
A61K9/19A61K31/56
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Quick Facts
Patent No.
US 9,974,750
App. No.
15/785,277
Granted
May 22, 2018
Kind
B1
Abstract

Synthesis of ifflaionic acid nanoparticles includes dissolving a powder of ifflaionic acid in an alcohol solution to form a first solution, adding the first solution to an aqueous solution under ultrasonic conditions to produce a sonicated solution, stirring the sonicated solution for a duration of time to produce a mixture, and freeze-drying the mixture to provide the ifflaionic acid nanoparticles.

Claims (9)

1. A method of synthesizing ifflaionic acid nanoparticles, comprising:

dissolving a powder of ifflaionic acid in an alcohol solution to form a first solution;

adding the first solution to an aqueous solution under ultrasonic condition to produce a sonicated solution;

stirring the sonicated solution for a duration of about 15 minutes to produce a mixture; and

freeze-drying the mixture to provide the ifflaionic acid nanoparticles, wherein the alcohol solution is added dropwise to the boiled water at a flow rate of about 0.2 ml/min to about 0.4 ml/min.

2. The method of synthesizing ifflaionic acid nanoparticles according to claim 1 , wherein the alcohol solution includes at least one of methanol and ethanol.

3. The method of synthesizing ifflaionic acid nanoparticles according to claim 1 , wherein the ifflaionic acid nanoparticles have a size ranging from about 0.5 nm to about 10 nm.

4. The method of synthesizing ifflaionic acid nanoparticles according to claim 1 , wherein the ifflaionic acid is obtained from Nuxia oppositifolia.

5. The method of synthesizing ifflaionic acid nanoparticles according to claim 4 , wherein the ifflaionic acid is obtained from an n-hexane fraction of aerial parts of the Nuxia oppositifolia.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2017
From: AL-MASSARANI, SHAZA MOHAMED ADEL, DR.; EL DIB, RABAB ABD EL MONEIM KHALIL, DR.; EL-GAMAL, ALI ALI, MR.; AWAD, MANAL AHMED GASMELSEED, MR.
To: KING SAUD UNIVERSITY
Reel/Frame 043876/0227 →