Methods of using indazole-3-carb oxamides and their use as Wnt/B-catenin signaling pathway inhibitors
This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.
1. A method of treating tendinopathy, the method comprising administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of a compound or pharmaceutically acceptable salt thereof having the structure of:
2. The method of claim 1 , wherein the tendinopathy is tendinosis.
3. The method of claim 1 , wherein the tendinopathy is tendinitis.
4. The method of claim 1 , wherein the tendinopathy is tenosynovitis.