IP Library › Patent Application 15790559
Patent Application
App. No. 15/790,559

CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE

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Quick Facts
Patent No.
US None
App. No.
15/790,559
Abstract

Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.

Claims (6)

1 .- 8 . (canceled)

9 . A method of reducing oxalate in a mammal, the method comprising administering a composition comprising oxalate decarboxylase crystals to the mammal in an amount sufficient to reduce the oxalate.

10 .- 16 . (canceled)

17 . A method of assaying a concentration of oxalate, the method comprising preparing a biological sample and measuring oxalate concentration in the sample using oxalate decarboxylase crystals or cross-linked oxalate decarboxylase crystals.

18 . A method of treating a disorder associated with elevated oxalate concentration in a mammal, the method comprising administering oxalate decarboxylase crystals to the mammal in an amount sufficient to reduce one or more symptoms associated with the disorder.

19 - 33 . (canceled)

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2019
From: SHENOY, BHAMI C.; CACHERO, TERESA G.; SHIN, JOHN; ZHANG, LEKAI; RASHID, AFTAB; GRUJIC, DANICA; PATEL, REENA J.; MCGRATH, MARGARET ELLEN
To: ALTUS PHARMACEUTICALS, INC.
Reel/Frame 048331/0221 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2019
From: LYNNE F. RILEY, AS CHAPTER 7 TRUSTEE OF ALTUS PHARMACEUTICALS, INC.
To: ALTHEA TECHNOLOGIES, INC.
Reel/Frame 048331/0600 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2019
From: AJINOMOTO ALTHEA, INC.
To: ALLENA PHARMACEUTICALS, INC.
Reel/Frame 048331/0641 →
CHANGE OF NAME Recorded Feb 14, 2019
From: ALTHEA TECHNOLOGIES, INC.
To: AJINOMOTO ALTHEA, INC.
Reel/Frame 048332/0319 →