USE OF AN OLEOGEL CONTAINING TRITERPENE FOR HEALING WOUNDS
An oleogel comprising a non-polar liquid and a powder containing triterpene is provided as an oleogel that may be used for healing wounds.
1 - 18 . (canceled)
19 . A method for healing a wound in patient in need thereof, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.
20 . The method of claim 19 , wherein the oleogel is administered to the wound during the reepithelialization phase.
21 . The method of claim 19 , wherein the triterpene fraction comprises between 1 weight-percent and 20 weight-percent of the oleogel.
22 . The method of claim 21 , wherein the triterpene fraction comprises between 6 weight-percent and 12 weight-percent of the oleogel.
23 . The method of claim 19 , wherein the fraction of betulin in the triterpene fraction is greater than 60 weight-percent.
24 . The method of claim 19 , wherein the fraction of betulin in the triterpene fraction is greater than 80 weight-percent.
25 . The method of claim 19 , wherein the triterpene fraction further comprises lupeol.
26 . The method of claim 25 , wherein the joint fraction of betulin and lupeol in the triterpene is greater than 80 weight-percent in the triterpene fraction.
27 . The method of claim 25 , wherein the joint fraction of betulin and lupeol is greater than 85 weight-percent in the triterpene fraction.
28 . The method of claim 19 , wherein the oleogel further comprises a nonpolar liquid.
29 . The method of claim 28 , wherein the nonpolar liquid is a plant, animal, mineral, or synthetic oil.
30 . The method of claim 29 , wherein the plant oil is a vegetable oil which is selected from one of the following: sunflower oil, olive oil, avocado oil, and almond oil.
31 . The method of claim 28 , wherein the nonpolar liquid consists of sunflower oil.
32 . The method of claim 28 , wherein the nonpolar liquid fraction comprises between 80 weight-percent and 99 weight-percent in relation to the total weight of the oleogel, and wherein the triterprene fraction comprises between 1 weight-percent and 20 weight-percent in relation to the total weight of the oleogel.
33 . The method of claim 19 , wherein the oleogel further comprises betulinic acid, oleanolic acid, and erythrodiol.
34 . The method of claim 19 , wherein the patient is a human.
35 . The method of claim 19 , wherein the method results in more rapid wound healing progress relative to a wound that is not treated with the oleogel.
36 . The method of claim 19 , wherein the method results in more rapid wound healing progress relative to a wound treated with Vaseline.
37 . The method of claim 19 , wherein the method results in complete healing of the wound.
38 . A method for promoting reepithelialization of a wound in a patient in need thereof, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.